Puffy breast is a term used to refer to cutaneous fly maggot disease, which is caused by fly larvae that are present in human skin tissue. Cutaneous fly maggot disease causes an inflammatory reaction in the patient's skin and cutaneous fly maggot disease can be treated with medication.

In the early stages of cutaneous fly maggot disease, nodules and abscesses appear on the surface of the skin, and pressure on the surface causes significant pain. These nodules rupture and are prone to visible fluid, and these nodules and abscesses do not disappear with compression.