The chemical name of saccharin is phthalimide, and the commercially available saccharin is actually the soluble sodium salt of phthalimide, referred to as saccharin sodium. The sweetness of saccharin sodium is about 450 ~ 550 times that of sucrose, so its1100000 aqueous solution has a sweet feeling, and it will be bitter when the concentration is high. The main raw materials for making saccharin are toluene, chlorosulfonic acid and o-toluidine, all of which are petrochemical products. Toluene is volatile, flammable and even explosive. 1997, a multi-generation feeding experiment in Canada found that a large amount of saccharin sodium intake could lead to bladder cancer in male rats. Therefore, the laws of developed countries, such as the United States, stipulate that when saccharin is used in food, the warning that "using this product may be harmful to health, and this product contains saccharin that can cause cancer in experimental animals" must be indicated on the label. Because eating saccharin is harmful to human health, some developed countries in the west strictly control the use of saccharin, and its control scale generally does not exceed 5% of the total sugar consumption, and it is mainly used for industrial purposes such as toothpaste.