2. Diabetic patients may need to adjust the dosage of antidiabetic drugs.
3. Patients with growth hormone deficiency caused by brain tumor or patients with a history of intracranial injury must closely monitor the progress or recurrence of their potential diseases.
4. At the same time, corticosteroids can inhibit the growth-promoting effect of growth hormone, so patients with ACTH deficiency should adjust the dose of corticosteroids appropriately to avoid its inhibitory effect on growth hormone.
5. A few patients may have hypothyroidism during growth hormone therapy, which should be corrected in time to avoid affecting the curative effect of growth hormone. Therefore, patients should regularly check thyroid function and give thyroxine supplement when necessary.
6. Patients with endocrine diseases (including growth hormone deficiency) may be prone to femoral head epiphyseal plate slippage. During growth hormone therapy, if there is claudication, we should pay attention to evaluation.
7. Because growth hormone can lead to excessive insulin status, it is necessary to pay attention to whether patients have impaired glucose tolerance.
8. Avoid overdose. Excessive injection of growth hormone will lead to hypoglycemia, followed by hyperglycemia. Long-term overdose may lead to symptoms and signs of acromegaly and other reactions related to excessive growth hormone.