Side effects with prednisone
The larger doses of this product are prone to cause diabetes, peptic ulcers and symptoms of Cushing's syndrome, the hypothalamus - pituitary - adrenal axis inhibitory effect is stronger. Complicated infection is the main adverse reaction.
Commonly known as ? Buffalo back, full moon face? is one of the side effects of using prednisone acetate tablets (prednisone), causing centripetal obesity, fat redistribution. So it is better not to take prednisone acetate tablets for a long time in non-essential cases. When stopping this type of medicine, you should also pay attention to the method of stopping the medicine? Decreasing discontinuation? , otherwise it will cause the disease rebound.
The use of prednisone acetate tablets (prednisone) in women during pregnancy may increase the incidence of placental insufficiency, neonatal weight loss, or stillbirth, and has been shown to be teratogenic in animal studies. Breastfeeding should not be practiced when the mother is receiving a high dose of the drug to prevent the drug from being excreted in the breast milk, resulting in side effects such as growth inhibition and adrenal suppression in the infant.
The use of glucocorticoids in elderly patients, especially post-menopausal women, is associated with high blood pressure and side effects such as osteoporosis.
The way to use prednisone
For different people with different diseases treatment, the specific dosage of prednisone acetate tablets are different:
1. Oral dosage is generally 5-10mg (1-2 tablets) at a time, 10-60mg (2-12 tablets) a day.
2. For autoimmune diseases such as systemic lupus erythematosus, gastric syndrome, ulcerative colitis, autoimmune hemolytic anemia, etc., the dosage of Prednisone Acetate Tablets is 40-60mg (8-12 tablets) per day, and the dosage will be gradually reduced after the condition is stabilized.
3. For drug dermatitis, urticaria, bronchial asthma and other allergic diseases, prednisone acetate tablets can be given 20-40mg (4-8 tablets) per day, after the symptoms are reduced to reduce the dosage, every 1-2 days to reduce 5mg (1 tablet).
4. In order to prevent organ transplantation rejection reaction, 100mg (20 tablets) per day is usually taken orally 1 to 2 days before the operation, and then changed to 60mg (12 tablets) per day one week after the operation, and then gradually reduce the dosage.
5. For the treatment of acute leukemia and malignant tumors, the dosage of Prednisone Acetate Tablets is 60-80 mg (12-16 tablets) orally per day, and the dosage will be reduced after the symptoms are relieved.
Identification method with prednisone
Take appropriate amount of fine powder of this product (about equivalent to 0.1g of prednisone acetate), add chloroform 50ml and stir, so that the prednisone acetate is dissolved, filtered, and the filtrate for the following tests.
(1) take the filtrate as a test solution; another take prednisone acetate control, add chloroform to make a solution containing 2mg per 1ml, as a control solution. According to the thin layer chromatography (Appendix VB) test, absorb the above two solutions each 5?l, respectively, point in the same silica gel G thin layer plate, with dichloromethane? Ether? Methanol? Water (385:60:15:2) as the unfolding agent, after unfolding, drying, drying at 105 ℃ for 10 minutes, cooled, sprayed with alkaline tetrazolium blue reagent, and immediately examined.
The color and position of the main spot shown by the test solution should be the same as that of the control solution.
(2) Take the remaining filtrate, set on a water bath to evaporate, the residue according to the identification under prednisone acetate (2), (3) test, show the same reaction.
Guess what you like:
1. side effects of prednisone
2. side effects of long term oral prednisone
3. side effects of hormones
4. what are the side effects of doing an enhanced ct
5. medications with the greatest side effects