Wei Daxun graduated from the acting department of the Central Academy of Drama in 2010.

In 2008, he starred in the interactive idol drama "Sophie's Diary", in which he played the role of "Xiao Nan".

On May 8, 2011, he acted in "Paper Boat and Candle Burning in the Sky" (also known as "Deadwood in the Spring"), playing the role of "Lai Huaisha", a doctor of the Blood Defense Brigade.

On October 20, he acted in the TV series "Mao Guanying", which landed on the prime time of the CCTV set, where he played the role of Mao Guanqing, which was authorized by Liu Siqi, who also served as a consultant, and won the 28th CCTV Awards. The drama was authorized by Liu Siqi, who personally acted as the advisor, and won the 28th Flying Apsaras Award for TV dramas, and the 12th Five Projects of Spiritual Civilization Construction Award for TV dramas, among other important awards. In the same year, he also acted in the Sino-Korean co-production "Chili and Kimchi", the youth inspirational drama "Police Cadet", and the web series "New Living Together" (also known as "Living Together"). He also played the role of Wu Yuzhang, a revolutionary in the late Qing Dynasty, in the film "The Xinhai Revolution", which won the Outstanding Feature Film Award at the 15th Chinese Film Huabiao Awards. At the same time, he played the lead role of the "second generation rich man" Wu Yi in the digital movie "Very Love".

On January 31, 2012, he appeared in the spy drama "The Crossbow", playing the villainous role of Li Nan. in July, he appeared in the TV drama "The Years of the Yak", playing the role of Yang Daxun, a Han Chinese Red Army man. in November, he appeared in the TV drama "Tonight's Angels Descend", playing the role of Yang Dahun, a Chinese Red Army man.

In 2013, he appeared in the TV drama "City Hunter", playing the role of a master forger, Fan Hong Ling. In July, he appeared in the Chinese-Korean co-production "One and a Half Summer".

On May 23, 2014, he officially signed a contract with JYP Entertainment, a South Korean agency, and on July 16, he appeared in "I am Fenqing" and was confirmed to star in the China-South Korea co-production "Hold Your Hand".

In 2015, Wei Daxun starred in the movie "Gardenia Blooms" directed by He Gui, playing the role of Zhang Jaichang, which was released on July 10, 2015 nationwide. Wei Daxun also starred in the TV series Because Love Has Happiness with Chen Weiting and other ****. In September of the same year, Wei Dahun starred in the idol spy drama Gray Geese.