Chronic kidney disease, you may not have heard of what kind of disease it is. Chronic kidney disease is a disease of kidney damage. What does it mean? To put it simply, it is a type of disease in which the physiological functions of the human body's kidneys gradually weaken or even terminate. It is scary to think about it. Kidney disease can be cured, and we cannot live without kidneys.
1. Chronic kidney disease knowledge
Chronic kidney disease (CKD) is now a public health problem worldwide, characterized by high incidence and poor prognosis. Poor and expensive. Proper early evaluation and interventional treatment of kidney disease can delay the progression of kidney disease in most patients, prevent the loss of renal function in some patients, improve the functions of other organs in patients with renal failure, and reduce complications.
Definition of kidney disease
The currently accepted definition is:
1 Renal damage (referring to kidney structural or functional abnormalities)_3 months, with or without Decreased glomerular filtration rate (GFR), manifested by one of the following:
Pathological abnormalities or
Indicators of renal damage, including abnormal blood or urine components, or imaging examinations Abnormal
2GFR60ml/(min·1.73m2)_3 months, with or without renal damage
So-called renal structural or functional abnormalities can be manifested in morphology, pathology or imaging Learning abnormality. Among them, we mainly obtain morphological or imaging information through renal ultrasound, while pathology mainly obtains renal tissue through renal puncture biopsy, and uses a variety of staining techniques to directly observe the renal structure under the microscope to obtain relevant information about the renal tissue. . Chronic kidney disease can manifest as glomerular atrophy, occlusion, tubulointerstitial fibrosis, etc. under microscopy. In addition, the components of urine and blood tests are abnormal, such as abnormal increases in urine protein, blood creatinine, urea, uric acid, and blood potassium.
Glomerular filtration rate is a clinical indicator of renal function. If any of the above abnormalities occur, it indicates kidney damage. Sometimes these abnormalities are transient and can be corrected, but if they continue not to be corrected for more than 3 months, we can clinically diagnose chronic kidney disease.
Staging of chronic kidney disease
After the diagnosis is clear, we still need to stage the disease according to the severity of the chronic kidney disease. According to the glomerular filtration rate (GFR) (unit: ml/(min·1.73 m2)), chronic kidney disease is clinically divided into 5 stages:
Stage 5 is also called End-stage renal disease (ESRD) or uremia.
Treatment of chronic kidney disease
Kidney diseases require different treatment options based on their etiology, pathogenesis, lesion location, pathological diagnosis and functional diagnosis. Existing treatment principles include removal of inducements, general treatment, treatment targeting the cause and pathogenesis, treatment of comorbidities and complications, and renal replacement therapy.
The dialectical treatment of Chinese medicine provides another treatment method for kidney disease. The effects of rhubarb, tripterygium glycosides, astragalus and other preparations have also been confirmed by many experimental studies, but each has its own disadvantages and limitations, and some may even cause nephrotoxicity. Huangkui capsules produced by Suzhong Pharmaceuticals have attracted more and more widespread attention from clinicians because of their safety and effectiveness in treating kidney disease.
The main active ingredient of Huangkui Capsule is extracted from the dried corolla of marshmallow flowers. The medicinal use of marshmallow flowers began in the Jin Dynasty, and was later used by successive generations of herbalists. It was recorded as Dusheng Powder Prescription in "Zhenglei Materia Medica". At that time, it was used by the people to treat boils, skin infections, etc. Later, the classic was inherited by Nanjing University of Traditional Chinese Medicine and Suzhong Pharmaceutical. After research and development and innovation, it was marketed as Huangkui Capsule, which is mainly used to treat various types of kidney diseases.
Huangkui capsules have been on the market for 15 years and have a unique clinical effect in reducing urinary protein. Evidence-based medicine also confirms that patients with chronic kidney disease (CKD) can reduce urinary protein by up to 48% in 24 weeks using Huangkui Capsules alone, and the efficacy is confirmed. So far, research on Huangkui Capsules has been extensive and in-depth and involves many fields, including chronic glomerulonephritis, IgA nephropathy, nephrotic syndrome, diabetic nephropathy, etc.
Numerous clinical trials have also confirmed that Huangkui Capsule can effectively inhibit intracellular oxidative stress, reduce renal tubule-interstitial damage, repair renal tissue damage, etc., and can effectively control urinary protein and serum creatinine levels in patients with kidney disease.
2. Complications of diabetic nephropathy
What are the complications of diabetic nephropathy
1. Proteinuria: Proteinuria is the first clinical manifestation of diabetic nephropathy. It is intermittent at first and then becomes persistent.
2. Edema: Due to large amounts of proteinuria, patients can develop edema. Once edema occurs, it indicates that diabetic nephropathy has progressed to the late stage.
3. Hypertension: Symptoms of hypertension appear late in patients, and one of the factors causing hypertension is water and sodium retention. Because high blood pressure can aggravate the development of renal lesions and the deterioration of renal function, attention should be paid to controlling high blood pressure.
4. Abnormal renal function: If a patient's diabetes can be well controlled, he or she can have proteinuria for many years without developing abnormal renal function. If not controlled well, azotemia and renal insufficiency will occur. In addition, diabetic nephropathy is often accompanied by diabetic retinopathy.
The kidneys are the largest metabolic organs of the human body. If the physiological functions of our kidneys are terminated, some physiological substances of the human body cannot be metabolized in time and cannot be excreted in time, so we suffer from Kidney disease is really terrible. It can also induce various complications and the consequences are very dangerous, so it must be treated in time.