Hyperuricemia is a chronic metabolic health problem, in which the concentration of urate in blood exceeds the normal level. Uric acid is a substance with poor solubility. When the concentration increases, urate crystals will precipitate in the blood. The urate crystals deposited in the blood may form deposits in the joint, and may cause inflammatory reactions in the joint, leading to joint swelling and pain. This is the problem of gout caused by high uric acid.
The attack of acute gouty arthritis caused by high uric acid is just one of the possible health hazards caused by high uric acid. Uric acid salt crystals will not only be deposited in joints to cause gout, but also in other parts of the body. Because the kidney is the main way of uric acid excretion, when the uric acid level is too high, urate deposition will also form in the kidney, which will slowly affect renal function and health, and may also cause stones and lead to acute kidney injury.
In addition to the possible impact on kidney health, even urate deposition in joints does not necessarily cause gout. In fact, there is a very common situation that urate slowly forms and deposits in joints, which will gradually form tophi and gradually affect joint health. The slow and uniform deposition of this urate will lead to the formation of chronic gout stones, but it usually leads to less acute gout attacks.
The formation of tophi is not limited to joints, but exists in many parts of human body, such as helix, synovial sac, tendon sheath, subcutaneous tissue and so on. It is also possible to form urate deposits, leading to the problem of tophi. These tophi may not only seriously affect the health of joints and articular cartilage, but also lead to skin ulceration at the deposition site and affect the health of related parts or tissues.
Many friends have the idea that although uric acid is high, it is not serious as long as there is no gout, let alone taking medicine to control uric acid level. But in fact this is a very wrong cognition. Whether gout attacks or not is not necessarily related to the harm of uric acid to health. For hyperuricemia, we should be more aware of the various chronic hazards mentioned above. These hazards are more easily overlooked than gout, but they are often more important.
Therefore, we should not only consider whether high uric acid causes gout, but also evaluate the risk of chronic gout and kidney health hazards caused by high uric acid level, and determine whether it is necessary to take medicine to control high uric acid according to the specific situation of uric acid level and health.
Uric acid is as high as 600, but there is no gout. Should I take medicine to control it? According to relevant guidelines and expert advice, it is generally believed that if the uric acid value exceeds 540μmol/L, whether gout occurs or not, drugs should be considered to control the problem of high uric acid. Such limits are not set out of thin air. On the one hand, the higher the uric acid value, the greater the harm to health if it is not controlled for a long time. On the other hand, if the uric acid value exceeds 540, it is usually controlled by life conditioning. It is also difficult to effectively control high uric acid by strengthening exercise. So generally speaking, if the uric acid value exceeds 600, even if it is not gout, it needs to be controlled by taking medicine. Especially in the following cases, we should pay more attention to drug control-