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Treatment of amyloidosis

1.Symptomatic treatment

To prevent amyloidosis from arising by targeting the primary disease, amyloidosis itself is a symptomatic treatment, patients with renal amyloidosis can undergo renal transplantation, with a longer survival period than other renal diseases, but the mortality rate in the early stage is higher, amyloidosis will eventually recur in the donor kidney, but some transplants can survive for 10 years.

2. Drug therapy

The drugs commonly used in treatment programs, including prednisone, melphalan or prednisone, melphalan, and colchicine, are undergoing clinical trials to compare these treatment programs. ①The stem cell transplantation program is still controversial. Digitalis can be used with caution in patients with amyloid heart disease who may develop arrhythmias. (iii) Heart transplantation has been successful, but strict patient selection is needed. ④ Colchicine is used to prevent acute attacks in patients with familial Mediterranean fever and has shown that no new amyloid appears and amyloidosis tends to decrease after treatment. ⑤ The application of transformed transthyretin, liver transplantation to resect the synthesis site of mutant proteins has been very effective in the treatment of hereditary amyloidosis.