Condition analysis: Advanced esophageal cancer often presents to the hospital due to difficulty in swallowing. The difficulty in swallowing develops progressively and may even lead to complete inability to eat. It is often accompanied by symptoms such as vomiting, upper abdominal pain, and weight loss. In the late stage of the disease, long-term insufficient food intake may be accompanied by obvious malnutrition, weight loss, cachexia, and complications such as cancer metastasis and compression. Symptoms such as hoarseness caused by cancer compressing the recurrent laryngeal nerve, pain caused by bone metastasis, and jaundice caused by liver metastasis. When tumors invade adjacent organs and become perforated, they can also cause mediastinal abscesses, pneumonia, etc. Some patients may occasionally feel a hard abdominal mass in the upper abdomen or feel enlarged supraclavicular lymph nodes. Opinions and suggestions: After patients with esophageal cancer are diagnosed, they often need treatment such as surgery, radiotherapy and chemotherapy. The treatment process will bring varying degrees of pain and annoyance to the patient. The patient's mental and nutritional status are closely related to the outcome and prognosis of treatment. Therefore, both patients and their families should communicate more with doctors, establish a correct concept of disease resistance, overcome the fear of disease, and cooperate with treatment with an optimistic attitude.