Methylcobalamin can treat peripheral neuropathy, which is in the instructions of methylcobalamin have clear indications, but also can treat megaloblastic anemia caused by vitamin B12 deficiency. Methylcobalamin is mainly endogenous vitamin B12, present in the blood, bone marrow fluid, compared with vitamin B12, methylcobalamin has a good effect on the improvement of neuronal conduction, and can promote the metabolism of nucleic acids, proteins, and fats through the methyl conversion reaction.

It acts as a coenzyme of methionine synthetase, which can promote the conversion of homocysteine to methionine, participate in the process of thymine synthesis from deoxyribonucleosides, and promote nucleic acid and protein synthesis, which can promote intra-axonal transport and axonal regeneration, as well as the formation of neural axons, and also prevent the degeneration of axons, thus repairing the damaged neural tissues. This drug can be given orally for three hours to reach peak blood oxygen concentration, it is absorbed and dose-dependent, in other words, normal larger doses may work relatively well, and methylcobalamin can be detected at one time from blood, adrenal glands, liver, stomach, and other tissues in high concentrations. When peripheral neuropathy is identified, methylcobalamin can be taken for treatment.