Pharmacological effects of senna:
Senna contains a significant laxative effect of substances, inhibit the intestinal absorption of glucose, sodium and water, so that the contents of the intestinal lumen increased dramatically, while increasing the tension of the large intestine, and then stimulate the intestinal wall reflexively make the small intestine and the colon peristalsis enhancement and lead to diarrhea.
Side effects of senna:
Senna may cause abdominal pain, vomiting, nausea, and in severe cases, upper gastrointestinal hemorrhage, manifested as epigastric pain, vomiting of coffee-like liquid or tarry stools.
Long-term users, because the side effects caused by overdose is more serious. Senna contains anthraquinones, this substance has an irritating effect on the intestinal mucosa, the long-term effect will cause pathological changes in the intestinal mucosa, induced colon black lesions, which is a precancerous lesion that can cause colon cancer.