Even if it was one or two in ancient times and one dollar today, the amount of Magnolia officinalis should be 24 grams, which is far greater than the 3~9 grams stipulated in the textbook of traditional Chinese medicine. It can be seen that if the dosage of Magnolia officinalis is used according to the regulations of traditional Chinese medicine, the expected effect will not be achieved.
Magnolia Officinalis, in Shennong Materia Medica Classic, has the theory of "stroke, typhoid fever, headache, cold and heat, palpitation, qi stagnation and blood stasis, and muscle death". In the textbook of traditional Chinese medicine, Magnolia officinalis is put in the dampness-eliminating medicine, which is bitter and warm, and belongs to spleen, stomach, lung and large intestine meridian, and has the effects of drying dampness, promoting qi circulation and relieving asthma. Clinically, it is mainly used for the syndrome of dampness and turbidity, gastrointestinal qi stagnation and lung qi obstruction, and the dosage is 3-9g.
In Treatise on Febrile Diseases, Magnolia officinalis was introduced six times; In Synopsis of the Golden Chamber, enter 1 1 time; In the whole treatise on febrile diseases, the dosage of Magnolia Officinalis 12 is half a catty (eight liang), five liang, four liang, three liang, two liang and one foot. It can be seen that different doses of Magnolia officinalis have different effects. Simple as follows.
Dose analysis of Baliang Houpu recipe
In Treatise on Febrile Diseases, the dosage of Magnolia Officinalis is half a catty (82 liang), including four prescriptions: Magnolia Officinalis Jiang Banxia Licorice Ginseng Chicken Soup, Dachengqi Soup, Magnolia Officinalis Sanwu Soup and Magnolia Officinalis Wuqi Soup.
Article 66 of Treatise on Febrile Diseases: "After sweating, people with abdominal distension should be treated with Shentang." Magnolia officinalis Jiang Banxia licorice ginseng soup: half a catty of magnolia officinalis, half a catty of Pinellia ternata, two ounces of licorice, one ounce of ginseng, half a catty of ginger, a bucket of water, three liters of boiling water and one liter of warm medicine, three times a day. This prescription is an effective prescription for treating spleen deficiency and abdominal distension. Professor Hao Wanshan from Beijing University of Chinese Medicine cited a case of ineffective use of Magnolia Officinalis, Ginger, Pinellia ternata, Glycyrrhiza uralensis and ginseng soup when he was talking about Treatise on Febrile Diseases. There are two reasons for the failure: first, the supply of Magnolia officinalis is tight, and second, the old pharmacist does not trust the young doctor. Later, he asked Ren Yingqiu, an old Chinese doctor in our hospital, to treat him. After adjusting the dosage of Magnolia Officinalis, he achieved good results. Mr. Ren Yingqiu said: Half a catty of Magnolia officinalis and half a catty of ginger, and one ginseng should be divided into two herbs. Half a catty of Pinellia ternata is good for removing the swelling, and spleen deficiency and abdominal distension are true. It can be seen that the dosage of drugs plays an important role in prescription, and it is also the key to achieve good clinical efficacy.
Dachengqi decoction comes from 208th's article in Treatise on Febrile Diseases: "Yangming disease has slow pulse. Although sweating does not hate cold, it will lead to heavy body, shortness of breath, abdominal distension and hot flashes. If you want to relieve it, you can attack the interior, and your hands and feet will sweat and swell." Dachengqi decoction: four taels of rhubarb, half a catty of magnolia officinalis, five pieces of immature bitter orange and mirabilite. Take a bucket of water, boil two things first, take five liters, take two liters of rhubarb, boil two liters, take mirabilite, and cook it once or twice on low heat. Take it at different temperatures and don't take the rest. From the original text, the main symptoms of using Dachengqi decoction are delayed pulse, sweating without aversion to cold, heavy weight, shortness of breath, abdominal distension, asthma, hot flashes, sweating on hands and feet and so on.
Article 8 of Synopsis of the Golden Chamber deals with abdominal distension, cold hernia and pulse syndrome: "Abdominal distension, fever for ten days, rapid pulse, normal diet, mainly Houpu Wuqi decoction." Houpu Wuqi Decoction consists of half a catty of Magnolia officinalis, three liang of licorice, three liang of rhubarb, ten jujubes, five pieces of immature bitter orange, two liang of cassia twig and five liang of ginger. Four liters of water in a bucket, eight times of warm water, three times a day. Vomiting, five-in-one plus Pinellia ternata; Li Xia, go to rhubarb; For those with severe cold, add half a catty of ginger.
Houpu Sanwu Decoction comes from the same article, article 10: "If the pain is closed, Houpu Sanwu Decoction is the main one." Comprise 82 pieces of magnolia bark, 42 piece of rhubarb and 5 pieces of immature bitter orange. Take two liters of water in a barrel, boil two flavors first, take five liters, take three liters of rhubarb in it, and take one to warm up.
All the above four parties use Magnolia Officinalis Baliang, and use Magnolia Officinalis to relieve abdominal distension and pain, but due to different pathogenesis, the compatibility of drugs is also different. Among them, the pathogenesis of Magnolia Officinalis, Ginger, Pinellia ternata and Glycyrrhiza ginseng soup is spleen deficiency and abdominal distension; The pathogenesis of Dacheng decoction is Yangming fu-organ syndrome, with delayed pulse, sweating without aversion to cold, abdominal distension, hot flashes and constipation as the main symptoms; Houpu Wuqi decoction is the syndrome of Taiyang Yangming. Guizhi decoction can relieve exterior symptoms by removing peony, while magnolia officinalis, rhubarb and immature bitter orange can regulate qi and relieve constipation. The main symptoms of Houpu Sanwu Decoction are abdominal distension and abdominal pain. Houpu and Fructus Aurantii Immaturus are used to regulate qi and help rhubarb relax bowels and stop diarrhea. It can be seen that Zhongjing's extensive use of Magnolia officinalis is mainly to relieve abdominal distension and fullness, and its pharmacological effect is mainly in the middle jiao abdomen.
Dose analysis of single magnolia prescription
In Treatise on Febrile Diseases, there are two prescriptions with a dosage of one foot: Maziren Pill and Houpu Dahuang Decoction.
Article 247 of Treatise on Febrile Diseases: "The pulse of nourishing yang is astringent, which means that the stomach is full of qi, astringent is urine, and astringent is loose stool, loose stool is cymbal, which is about spleen. Maziren Pill treats it." Ma Zi Wan Ren Prescription: two liters of Fructus Mazzi, half a catty of Radix Paeoniae Alba, half a catty of Fructus Aurantii Immaturus, one catty of rhubarb, one foot of Magnolia Officinalis, one liter of almond, six-flavored honey pills, as big as buttonwood, take ten pills three times a day, step by step, depending on your knowledge. This prescription focuses on relaxing bowels. Judging from the dosage of other drugs in the prescription, one foot of Magnolia Officinalis is not less than the dosage of Radix Paeoniae Alba, Fructus Aurantii Immaturus and Radix et Rhizoma Rhei, and it should be between half a catty and four liang.
Article 17 of Synopsis of the Golden Chamber says: "Houpu Dahuang Decoction is the main prescription for people who are full of milk." Magnolia officinalis and rhubarb decoction: one foot of magnolia officinalis, six taels of rhubarb, four pieces of immature bitter orange, five liters of water, boiled for two liters, and then taken at different temperatures. In terms of dosage, the dosage of Magnolia Officinalis, Rhubarb and Fructus Aurantii Immaturus is greater than that of Xiaochengqi Decoction. Therefore, in addition to "breast augmentation", when there is constipation, the heavy dose of Magnolia officinalis should be used together with rhubarb and immature bitter orange, which has a laxative effect. Therefore, the amount of Magnolia officinalis in Han Dynasty should be no more than eight taels to reflect the therapeutic effect of the prescription, but it will never be less than Xiaochengqi Decoction.
Dose Analysis of Erzhi Wuwei Houpu Recipe
In Treatise on Febrile Diseases, there are six prescriptions of Magnolia Officinalis * * * 22, 32, 42 and 52. Among them, two kinds of Magnolia Officinalis are Guizhi Thickening Puxingzi Decoction and Xiaochengqi Decoction respectively; Banxia Houpu Decoction is used for three purposes; Gardenia and Houpu Decoction is used in four pairs with Fructus Aurantii Immaturus, Bulbus Allii Macrostemon and Guizhi Decoction. It's Houpu Mahuang decoction. It took five taels.
Guizhi Thickening Puxingzi Decoction comes from article 18 of Treatise on Febrile Diseases: "It is better to use Chuanjia Thickening Puxingzi as Guizhi Decoction." Article 43 of Treatise on Febrile Diseases: "Taiyang disease, slight asthma in the lower abdomen, which is not solved on the surface, is mainly treated by Guizhi Thickening Puxingzi Decoction." According to the original text, the main function of Magnolia Officinalis is to lower lung qi and help almond to relieve asthma.
Xiaochengqi decoction consists of four tablets of rhubarb, two tablets of magnolia officinalis and three tablets of immature bitter orange. 208th in Treatise on Febrile Diseases: "If the abdomen is full, it can be slightly adjusted with Xiaochengqi Decoction to prevent leakage." Article 18 of Synopsis of the Golden Chamber, Vomiting, Syndrome Differentiation and Treatment of Deceptive Pulse: "Deceptive words accompanied by dry stool, mainly Xiaochengqi decoction." It can be seen that Xiaochengqi decoction focuses on relaxing bowels, and Magnolia officinalis is used in pairs, and it is compatible with Fructus Aurantii Immaturus to reduce qi and help rhubarb relax bowels.
Banxia Houpu Decoction comes from Article 5 of Synopsis of the Golden Chamber: "Banxia Houpu Decoction governs the throat of a woman." The prescription is: Pinellia ternata 1 l, Magnolia officinalis 3 liang, Poria cocos 4 liang, ginger 5 liang, and perilla leaf 2 liang. It can be seen that the three pairs of magnolia officinalis have the function of reducing qi and resolving phlegm.
Gardenia and Houpu Decoction comes from article 79 of Treatise on Febrile Diseases: "Gardenia and Houpu Decoction is the main prescription for people who are upset and full of stomachs after typhoid fever." Remove fullness with Siliang Magnolia Officinalis and Fructus Aurantii Immaturus, and remove annoyance with Gardenia. The fifth syndrome of chest obstruction, heartache and shortness of breath in Synopsis of the Golden Chamber: "Chest obstruction is swollen in the heart, qi is trapped in the chest, the chest is full, and the heart is robbed under the threat." Magnolia officinalis in treating thoracic obstruction. It can be seen that the 4 magnolia officinalis of Zhongjing mainly acts on the upper chest coke to eliminate abdominal distension and fullness.
Houpu Mahuang Decoction comes from the article 10 in Synopsis of the Golden Chamber: "Houpu Mahuang Decoction is the master of cough floating pulse." The prescription is: five liang of magnolia officinalis, four liang of ephedra, gypsum chicken, half a catty of almond, half a liter of Pinellia ternata, two liang of dried ginger, two liang of asarum, one liter of wheat and half a liter of Schisandra chinensis. The disease is characterized by cough and asthma, drinking water due to wind-cold and lung-stomach heat, which is regarded as severe asthma. According to another sentence in Volume 10 of Thousand Golden Prescriptions, "The breath of coughing is full of throat, which is not conducive to the sound of water chickens", it can be seen that the main function of using Magnolia officinalis is to remove chest fullness, reduce phlegm and reduce qi.
Keep in mind the proportion of prescription drugs
Therapeutic effect is the key to the survival and development of traditional Chinese medicine. The ancients said: "The secret of Chinese medicine not spreading lies in quantity." Under the premise of syndrome differentiation and correct prescription selection, the most important factor restricting the curative effect is dose. The ability to control the dosage of traditional Chinese medicine is an important index to measure a doctor's clinical level.
There are many links in the treatment of TCM, such as syndrome differentiation, prescription selection and medication. Correct syndrome differentiation and correct prescription selection. If the dosage ratio of drugs is wrong, it will also affect the curative effect. Therefore, it is necessary to follow the proportional relationship of drug compatibility of all parties to achieve energy efficiency.
According to the analysis of the dosage of Magnolia Officinalis in Treatise on Febrile Diseases, Magnolia Officinalis mainly acts on the upper middle jiao and the second jiao, and is mainly used for asthma and cough syndrome caused by qi stagnation of the spleen and stomach and lung, mainly for reducing turbidity. In particular, Xiaochengqi decoction, Houpu Sanwu decoction and Houpu Dahuang decoction have the same components, but the diseases and syndromes treated are different due to different doses of drugs, which should attract the attention of clinical workers.
While studying the methods of syndrome differentiation and treatment of Treatise on Febrile Diseases and the law of compatibility of prescriptions and drugs, we should keep in mind the proportion and dosage of prescriptions and drugs, trace back to the source and inherit the experience of sages, so as to apply them freely in clinic and improve the curative effect.
In addition, regarding the dosage, quantity and balance of drugs in the Han Dynasty, research by authoritative departments of the state confirmed that some people suggested that one or two of them were15.625g today, while others suggested that they were13.8g.. There is little difference between them, but they are rarely used in clinic. Even if it was one or two in ancient times and one dollar today, the amount of Magnolia officinalis should be 24 grams, which is far greater than the 3~9 grams stipulated in the textbook of traditional Chinese medicine. It can be seen that if the dosage of Magnolia officinalis is used according to the regulations of traditional Chinese medicine, the expected effect will not be achieved.