After long-term clinical observation, chronic pharyngolaryngitis generally does not turn into cancer. However, if the following situations occur, it should be highly valued; 1. Patients who are poorly treated or continue to be exposed to certain irritating substances, especially long-term smokers over 40 years old, may lead to pharyngeal wall and laryngeal cancer due to precancerous lesions such as abnormal proliferation of the mucosa of the pharynx and formation of leukoplakia.　　2. Early morning aspiration of hemorrhagic nasal mucus from the back of nose, i.e. retracted nasal mucus with blood, is often an early signal of nasopharyngeal cancer.　　3. Early symptoms of esophageal cancer patients can also be manifested as discomfort in the throat or burning sensation in the chest, which is often easy to be confused with chronic pharyngolaryngitis, but these patients are usually accompanied by dysphagia.　　Therefore, once diagnosed with chronic pharyngolaryngitis, you should actively cooperate with your doctor, speak as little as possible, and lower your voice as much as possible, in order to get well as soon as possible.　　Popular Health, Issue 3, 2005, Gao Chundongwen