Doctor Octopus (aka "Doc Ock"), formerly known as Dr. Otto Octavius, is the villain in the "Spider-Man" comics. He was created by writer Stan Lee and artist Steve Ditko. He is the first The first appearance was in The Amazing Spider-Man (July 1963). Stan Lee said that Doctor Octopus is one of his favorite villains in the "Spider-Man" comics. When Doctor Octopus first appeared, his name was spelled "Octavious". Despite his octopus-like name, he would rather be human. Doctor Octopus is a short, fat man who uses four powerful mechanical accessories. He is a highly intelligent mad scientist who wants to prove his own genius and destroy Spider-Man. Many consider him to be Spider-Man's greatest foe. Like the Green Goblin, he is Spider-Man's former great friend. Interestingly, Doctor Octopus was a beauty in Spider-Man: Shattered Dimensions.

During the long battle with Spider-Man in the later period, Doctor Octopus's body was severely damaged, so he exchanged souls with Spider-Man in "Spider-Man: Doomsday" and became the ultimate Spider-Man. (See Ultimate Spider-Man for details) Vows to be better than Peter, raises an army, threatens the mayor, puts the city under surveillance, falls out with the Avengers, breaks up with Mary Jane, and breaks up with Anna Marie Ya falls in love (blocking a building for her), helps Peter get his PhD, sets up Parker Enterprises, and helps Aunt May install artificial bones. Originally everything was perfect, but was caught off guard by the Green Goblin's underground army. When everything was on the verge of destruction, Peter's soul returned. Doctor Octopus realized that Peter was the real ultimate Spider-Man, and finally chose to sacrifice and delete his memory. , returning the body to Peter.