1, digestive manifestations: this is the most common symptoms of liver disease, most of the liver disease, such as: nausea, anorexia greasy, poor appetite, generalized fatigue, etc., may be vomiting, diarrhea, splenomegaly and other symptoms. Such symptoms may also be associated with hepatogenic ulcer disease caused by chronic liver disease, portal hypertensive enteropathy, and so on.
2, hepatic discomfort: among all the symptoms of liver disease, hepatic discomfort and hepatic pain are more specific, when such symptoms are suspected to be caused by liver disease, traumatic factors should be excluded. Occasionally, temporary hepatic pain and discomfort may occur in normal people, which is relatively rare. Liver discomfort and pain in the liver area are often related to the compression of hepatic pericardium by hepatomegaly, and the nature and degree of pain in the liver area are different with the regression of the disease and the aggravation or alleviation of hepatomegaly. Hepatocellular carcinoma is generally progressive aggravation, which is mainly caused by the increasing size of hepatocellular carcinoma tumor compressing the hepatic peritoneum.
3. Systemic manifestations: weakness and easy fatigue are the most common systemic manifestations. Some patients with liver disease can be accompanied by different degree of jaundice, which is the most specific symptom of liver disease (except physiological jaundice in children), manifested as yellow urine, yellow eyes and yellow skin. Itching of the skin occurs when jaundice is too high.
4, liver palm spider nevus: many chronic liver disease will appear liver palm, spider nevus, liver disease face, especially cirrhosis patients are more common. But the liver palm and spider nevus has no specificity, in normal people can also see, so can not people have spider nevus or liver palm is said to be a symptom of liver disease.
5, ascites: ascites usually occurs in the advanced stage of liver disease or extremely serious condition, such as cirrhosis, ascites means that the cirrhosis has entered the advanced stage.
6, bleeding tendency: liver disease bleeding phenomenon embodied in the liver function is reduced, so that coagulation factor synthesis is reduced. It is easy to cause bleeding gums, bleeding hemorrhoids, gastrointestinal bleeding, etc., and it is difficult to stop bleeding.
7, portal hypertension: portal hypertension refers to the elevated pressure of the portal venous system. It often causes esophagogastric fundus varices, which is the main cause of gastrointestinal bleeding. Once bleeding occurs, combined with bleeding tendency condition is often more dangerous, is one of the main causes of liver disease (mainly refers to cirrhosis, advanced liver cancer) death.
8, hepatic encephalopathy: this is the development of liver disease to the end stage of the performance, the symptoms are extremely dangerous, is the most important cause of liver disease death.
Early Symptoms of Liver Disease
Darkness of the face: unlike sun-tanned skin, the condition is dark and glossless on the face; in addition, severe dark circles under the eyes are all early symptoms of patients with chronic liver disease, most of which is chronic hepatitis B.
Yellow skin: people who have never suffered from hepatitis, early symptoms of liver disease patients in the cold, fever, nausea, vomiting, liver pain, extreme fatigue, suddenly appeared in the eyes and skin yellow, it shows that the acute jaundice hepatitis; chronic hepatitis patients, if the jaundice, indicating aggravation of the disease.
Liver palm: the color of the palm of the hand is very different from that of a normal person. The color of the palm of a normal person is red and moist, while the palm of a patient suffering from liver disease is whitish and bloodless.
Spider nevus: there is a red spot in the middle, surrounded by blood filaments, similar to the symptoms of mosquito bites, when the center of the nevus with a thin rod end pressure, the whole nevus disappears, let go and then appear, this early symptoms of patients with liver disease can be identified with other vascular nevi. According to the introduction, the male body surface with spider nevus, 85% of people can have different degrees of liver tissue lesions, of which about 30% for cirrhosis.
Three principles of treatment of liver disease
The first is anti-virus. The second is to improve immunity. The third is to restore liver function, mastering these three principles, hepatitis B in order to talk about the problem of turning negative. Restore liver function, both to restore the liver detoxification function, in terms of pathological changes, is to improve the detoxification function. Relying solely on the Japanese imported "chitosan" for the treatment of hepatitis B is not possible, after all, it is not a drug, it is a kind of immunity enhancement, together with better antiviral drugs, found that many patients with hepatitis B have turned negative. The Ministry of Health scholars also talked about mastering these three principles, the conversion rate can be as high as about 20%.
The latest research on hepatitis B suggests that there are two kinds of hepatocellular changes in hepatitis B. One kind of autoimmune system problems, the virus overflowed from the cell membrane to the plasma, causing autoimmune antigen-antibody complex formation, which caused damage to the hepatocytes: the other kind of discovery is that the hepatitis B virus parasitizes the hepatocytes. The reason why it is difficult to treat viral diseases in medicine is that drugs usually only act on the receptors of the cell membrane, and it is difficult to enter into the cells. Hepatitis B virus into the liver cells, liver function is not reduced when they become carriers of the virus, HIV carriers is this reason. HIV parasites in the immune cells, but it has not yet affected many functions, the virus it is involved in the integration of hepatocyte genes, and its components and hepatocyte DNA, RNA gene integration, so many scholars believe that hepatitis B is not possible to turn negative, can not be turned, because its genes have been involved in the inside to go.
Recently it was also found that the hepatitis B virus itself cannot cause cell death. The cell membrane has a physiological function called encapsulation, the cell itself can discharge intracellular foreign matter called encapsulation, if the cell membrane is normal, it does deformation movement, it retracts a little bit, the virus flashed to the outside of the cell membrane, and then the cell membrane in the return to normal, the virus pushed back to the outside of the cell membrane. At this point, phagocytes surround and engulf it again, and the cell returns to normal. Where does the problem occur in hepatitis B patients? Hepatitis B virus into the liver cells to participate in the gene integration, the cell membrane function declines, it is in the process of the packet spit changes: the packet spit power can not be successfully discharged in the virus outside the cell membrane, on the contrary, the virus is embedded in the cell membrane stuck in the cell can not be separated. Macrophages in the human body, this cell is very large, it found that food to eat, the cell membrane to wrap, it (macrophage) can not eat, it will release a large number of lysosomal enzymes, as a result of the dissolution of the hepatocyte membrane, so that the liver cell death. Virus formed in the inside of the active cells, which caused connective tissue proliferation, portal hypertension, cirrhosis, induced liver cancer, so that it has changed its pathology.
According to incomplete statistics, China's existing hepatitis B virus infected more than 100 million people, there are 20 million chronic hepatitis B patients, is a real "hepatitis B country". China's existing liver cirrhosis, liver cancer and other serious diseases, more than 80% are developed from hepatitis B.
Experts suggest that "prevention" is not only reflected in the infection before, but also must be carried out to the different stages of the disease after the infection, prevention and treatment properly can still protect health. As Andy Lau said, he found out at a young age that he was a hepatitis B virus carrier, he checked his body every three months, correctly follow the means of hepatitis prevention and treatment to do, everything is still very healthy.
The different stages of chronic hepatitis B patients have to have corresponding preventive measures, for example, hepatitis B virus carriers should be long-term observation, regular follow-up, timely review, pay attention to the direction of the development of lesions; in the morbidity state of hepatitis B patients should be treated in a timely manner, to prevent lesions to the cirrhosis of the liver direction of the development of chronic active hepatitis in line with the indications for antiviral therapy, in the premise of the economic conditions permit, available Interferon or nucleoside antiviral therapy, for patients who do not meet the antiviral treatment can be carried out first to protect the liver and reduce the enzyme yellow auxiliary treatment.
Chronic hepatitis B patients should be regular comprehensive review, especially those who receive antiviral treatment, to the hospital can be conditioned to carry out liver histology examination; cirrhosis patients can be regular examination of the gastroscope, regular imaging examination, to see whether there is cancerous; advanced cirrhosis, if possible, can be carried out liver transplantation.
Important factors inducing fatty liver
Obesity
Liver Disease Picture Gallery (16 pictures)
Half of the people can have mild fatty liver, but the incidence of fatty liver in patients with severe obesity can reach 61%.
Obese people due to the increase of adipose tissue in the body, the release of fatty acids and free fatty acids in the body increased, became the body's main energy supply material, and the utilization of glucose is reduced. Under normal circumstances, glucose utilization is reduced, elevated glucose levels in the blood can stimulate insulin secretion to inhibit the release of free fatty acids, but when a large increase in body fat, even if inhibited by insulin, the release of free fatty acids or the absolute amount of increase in the fatty acid release, so that excessive fatty acids into the liver synthesized as triglycerides, and then the formation of fatty liver. This is why obese people are prone to fatty liver of the basic principle.
In addition, the intake of high-calorie diet in obese patients is also a factor in the formation of fatty liver. The accumulation of fat in the liver is directly proportional to body weight, and after weight control in obese patients, the degree of their fatty liver is reduced. On the contrary, weight increase, fatty liver also aggravated. This shows that the fatty liver of obese patients is part of the total body fat. Reducing the aid of nutrients and controlling body weight can improve fatty liver.