Wild watermelon soaked in wine can treat rheumatism, arthritis, and joint swelling and pain.

Soak wild watermelon in medicinal wine, dip a cotton swab in the medicinal wine, and apply it lightly on the painful areas of the waist and legs, three times a day, and keep using it every day. The joints will feel soothing and warm, and the coldness in the body will be dispelled. Wild watermelon seedlings are annual herbaceous plants, all covered with fine soft hairs of varying density. The stem tip is soft, upright or slightly recumbent. The base leaves are nearly rounded, with toothed edges. The middle and lower leaves are palmate, with 3 to 5 deep lobes. The middle lobes are larger. The lobes are obovate-oblong, with blunt apex, and the edges have pinnate notches or large serrations. The flowers are solitary in the leaf axil, and the pedicel is 2 to 5 cm long; the bracts are numerous, linear, and ciliate; the calyx is 5-lobed, membranous, with green longitudinal veins; the petals are 5, light yellow, with a purple heart; there are many stamens and filaments. They combine to form a cylinder and wrap the style; the ovary has 5 cells, the top of the style has 5 lobes, and the stigma is capitate. The capsule is spherical and has long hairs. The seeds are dark brown, rough and hairless when mature. The flowering period is from July to September, wild or cultivated.