The symptoms of syphilis are hard chancre, flat warts, enlarged lymph nodes, ocular syphilis, and worm-like alopecia.1. Hard chancre: This is a typical symptom of early syphilis. At first, it just appears as a small bump, which is painless and itchy. Even if it is left untreated for 3~8 weeks, it will fade naturally. There will be no trace or only a slight scar after fading. However, the chancre is accompanied by a small amount of plasma secretion containing a large number of syphilis viruses, which is highly contagious.2. Flat warts: this is a typical symptom of stage 2 syphilis. Generally, after the chancre subsides for a period of time, flat papules will appear. They are round or irregular in size, like needles or grains of rice, which are flat warts. They can appear on the skin of the limbs and trunk, but most will appear on the vaginal mucosa with redness, swelling, vesicles and oozing. If sexual intercourse occurs, it is also highly contagious.3, swollen lymph nodes: 7 to 10 weeks after syphilis infection, the syphilis virus will enter the blood system through the lymph nodes and multiply rapidly in the body. At first, the symptoms of swollen lymph nodes will appear near the rash, and then the whole body will have swollen lymph nodes, accompanied by low-grade fever, headache, muscle pain and other manifestations.4, ocular syphilis: when the condition of syphilis is serious, it will also invade the eyes, resulting in ocular syphilis, accompanied by decreased visual acuity, redness and swelling of the sclera, congestion, photophobia, tearing and other symptoms.5, worm-eaten alopecia: Syphilis can also lead to worm-eaten alopecia. The onset site is usually at the back of the head, and the boundary is not clear. Even without treatment, new hair can grow after a while. Avoid infection: Syphilis is a sexually transmitted disease caused by syphilis spirochete infection, which requires an infectious source and a transmission route to spread. Therefore, patients should pay attention to cleanliness and avoid unprotected sexual contact to avoid infecting others. Timely treatment: Once diagnosed with syphilis, patients should actively cooperate with doctors to carry out standardized treatment, so as to avoid delaying the condition and affecting health. Regular review: Generally speaking, the first year after the cure of syphilis, the patient should go to the hospital every three months to review; the second year after the cure of syphilis, the patient should go to the hospital every six months to review; from the third year after the cure of syphilis, the patient should go to the hospital every year to review, so as to ensure that the syphilis is completely cured.