Reason: Certain nitrosamine compounds, such as N- nitrosamine and N- nitrostetrahydropyrrole, can produce carbocation to react with biological nucleophiles (such as DNA or enzymes) in cells. Once such nucleophilic substitution occurs in a key part of a biomacromolecule, it may destroy the normal function of cells and lead to cell canceration or apoptosis.

Other applications of sodium nitrite:

1, chromatographic analysis. Dot analysis is used to determine mercury, potassium and chlorate.

2. Analytical reagents are used as chromogenic agents, antimicrobial agents and preservatives in the processing of meat products. It has applications in bleaching, electroplating and metal treatment, and is called industrial salt.

Extended data:

A, the use of sodium nitrite matters needing attention:

1, sodium nitrite is toxic, and the toxic side effect of excessive intake is to paralyze the vascular movement center, respiratory center and surrounding blood vessels and form methemoglobin. Acute poisoning is characterized by general weakness, headache, dizziness, nausea, vomiting, diarrhea, chest urgency and dyspnea; Examination showed that the skin and mucosa were obviously cyanotic.

2. The standard for safe intake of sodium nitrite by human body issued by the Scientific Committee of World Food Hygiene 1992 is 0 ~ 0.1㎎/㎏ body weight; If converted into nitrite, its standard is 0 ~ 4.2 ㎎/60 kg body weight. If it is used and eaten according to this standard, it will not cause harm to human body.

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