No.

Do not apply toothpaste if the corners of your mouth are irritated or blistering. After applying toothpaste, although the presence of mint can relieve itching, it can easily lead to infection and inflammation of the corners of your mouth. Blistering at the corners of the mouth is caused by the herpes simplex virus, which is a viral infection. You can apply acyclovir ointment locally, 5-6 times a day, and the herpes will subside on its own in about a week.

If after applying toothpaste, the toothpaste has an irritating effect, which may easily aggravate herpes. The main ingredient in toothpaste is a friction agent, which has no effect on treating the herpes virus.

Extended information:

Notes:

1. Adjust your diet. Try not to eat spicy, irritating or hot foods that are easy to cause internal heat. Inflammation will not only cause blistering in the mouth, but also cause other diseases. You should eat more vitamin-rich vegetables, fruits, and protein-rich foods in your daily diet. Fish, milk, etc.

2. Supplement vitamin B.

3. Exercise regularly, stay up less late, and enhance immunity.

4. When your mouth has blisters, you can try applying erythromycin eye ointment. This is a very cheap over-the-counter ointment that has bactericidal and anti-inflammatory effects. Apply it several times a day to reduce the blisters on your mouth. It will get better soon.

5. Naturally extracted aloe vera gel has no toxic side effects and has obvious auxiliary effects on small wounds, mouth ulcers, etc. It can effectively reduce inflammation and sterilization, and promote wound healing.

Baidu Encyclopedia - Burning in the Mouth

Baidu Encyclopedia - Toothpaste

People's Daily Online - Burning in the Mouth is Always Annoying. What to Do if the Mouth Is Burned