Drinking modern people socialize in a way, at the table seems to have no finish, of course, this is not absolute, drink in moderation, drink more hurt, drink properly health. To know what is the best way to relieve alcohol after drinking, what is the fastest way to wake up and drink? We must first understand how alcohol is actually absorbed and metabolized in the human body?
First, the absorption of alcoholSpirits are generally absorbed into various tissues and organs of the body through the mouth, esophagus, stomach, intestinal mucosa, and 5min can appear in the blood, to be 30?60min, the blood alcohol concentration can reach its highest point. Drinking alcohol on an empty stomach has a much higher absorption rate than on a full stomach. The stomach absorbs 10-20% of alcohol and the small intestine 75-80%. 60% of the alcohol consumed at one time is absorbed within one hour, and all of it can be absorbed in two hours.
Two, the metabolism of alcoholHow does our body metabolize alcohol? Alcohol metabolism in the body mainly depends on two enzymes: one is ethanol dehydrogenase, the other is acetaldehyde dehydrogenase. Ethanol dehydrogenase can take off the two hydrogen atoms in the alcohol molecule, so that ethanol is broken down into acetaldehyde. And acetaldehyde dehydrogenase can take off the two hydrogen atoms in acetaldehyde, so that acetaldehyde is broken down into acetic acid, and then broken down into carbon dioxide and water out of the body.
Three, the excretion of alcoholAlcohol in the body oxidation and excretion rate is slow, so it is absorbed and accumulated in the blood and tissues (brain tissue in the concentration of alcohol is 10 times the concentration of blood alcohol). The vast majority of alcohol is metabolized mainly in the liver, and only a very small amount (about 2% to 10%) of alcohol is not oxidized and decomposed and excreted directly in the urine via the kidneys, or exhaled from the respiratory tract via the lungs, or eliminated by evaporation via the sweat glands of the skin. Therefore, the alcohol concentration of a person's exhaled breath is much lower than the actual concentration of alcohol in the body.
Alcohol metabolism process, will also be accompanied by changes in the ratio of NADH and NAD (NAD is a cofactor and hydrogen acceptor), galactose tolerance decreases, triglyceride synthesis increases, lipid peroxidation increases the complexity of the changes, so clinically there has been a post-drinking hypoglycemia and gout attacks, and tend to be long term excessive alcohol consumption of people with high triglyceride levels.
Four, the best way to solve the alcoholMethod one
Delay the absorption of alcohol, as far as possible to reduce the blood alcohol content. Alcohol can be quickly absorbed in the stomach and small intestine in large quantities, if the stomach has food, can reduce the stimulation of the stomach lining, delay gastric emptying, reduce the osmotic absorption of alcohol. Therefore, it may be worthwhile to eat something before drinking.
Method two
Dilute the alcohol to allow slow absorption. There is a bad habit in the society, is to spell alcohol, big mouth fierce drinking caused by blood alcohol concentration rise sharply, people will be more prone to drunkenness, so it is recommended to drink slowly in small sips. In addition, you can drink more water, drinks (do not drink carbonated beverages, such as cola, soda, etc., these can accelerate the absorption of alcohol), to dilute the alcohol concentration, to prevent drunkenness.
Method 3
Don't mix many kinds of alcohol. Various kinds of alcohol have different compositions and contents, different mechanisms of intoxication, and when several kinds of alcohol are mixed, people don't know how much they actually ingest. In addition, the body has to react to several kinds of alcohol at the same time, and it is easy to get disorganized, leading to accelerated drunkenness.
Method 4
After drinking a lot of alcohol it is best to use fruit juice as a wake-up call, especially orange juice and apple juice, they contain fructose, which can help the alcohol burn better and play a good role in relieving alcohol.
Method five
(1) Drink glucose (50%):
The effect is: ① accelerate the discharge of ethanol. After drinking glucose injection, blood glucose rises, blood volume increases, accelerating the body's liquid through the kidneys of the urine discharge; ② accelerate the decomposition of ethanol. Glucose provides energy to accelerate the decomposition of alcohol metabolism, and has the effect of liver protection; ③ correct hypoglycemia.
(2) promote alcohol metabolism drugs:
Metadoxine. Metadoxine is an activator of acetaldehyde dehydrogenase, and can antagonize the decline in activity of ethanol dehydrogenase (ADH) caused by acute and chronic alcoholism; accelerate the excretion of ethanol and its metabolites acetaldehyde and ketone bodies through the urine, which belongs to the alcohol metabolism promotion drugs.
It can counteract the decrease of ATP and intracellular reduced glutathione (GSH) level caused by acute ethanol intoxication, maintain the balance of the body's antioxidant system, antagonize the oxidative stress caused by acute and chronic alcohol intoxication, improve the damage of liver function caused by drinking and improve the psychological behavioral anomalies caused by alcohol intoxication, and it can be used in patients with moderate and severe intoxication, especially those accompanied by aggression and emotional anomalies. It can be used in patients with moderate or severe intoxication especially with aggressive behavior and abnormal mood. Appropriate rehydration and supplementation of vitamin B1, B6, C is conducive to the oxidative metabolism of alcohol.
(3) Pueraria lobata, Pueraria lobata
Pueraria lobata has the effect of relieving alcohol and protecting the liver, and Pueraria lobata has the effect of generating fluids and quenching thirst. Drinking Pueraria lobata tea before drinking can protect the gastric mucosa; after drinking, soaking some Pueraria lobata and Pueraria lobata can increase the amount of sweating and urination and accelerate the discharge of alcohol.
In short, a series of alcohol poisoning symptoms in the human body is caused by the high level of alcohol in the blood. Therefore, the concentration of alcohol in the blood should be diluted to slow down the absorption of alcohol, and promote its decomposition in the body and accelerate the excretion of alcohol, in order to achieve the purpose of alcohol detoxification. The correct way to relieve alcohol is to accelerate the metabolism of alcohol, on the one hand through sweating and on the other hand through urination. For the heavier and more serious alcoholism must be immediately rescued.