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How is lipoma formed?
Lipoma is a benign tumor formed by the proliferation of mature adipose tissue. More common in adults aged 40 ~ 50. The tumor is soft; Round or lobulated; It is located under the skin and can be pushed. Tumors vary in size, as small as dates, and can only be touched by hand. Large tumors can make the skin surface bulge, but the surface skin is normal. Single or multiple tumors can be found anywhere on the body surface, especially on the shoulders, back and abdomen. There are many unconscious symptoms. Angiolipoma is a special type of lipoma, which is more common in young people. It mainly occurs in the lower limbs, and you can feel pain and tenderness when you touch it. According to the pathogenesis and modern biomolecular theory, etiology finally summarizes the root causes of various types of lipoma. "Lipogenic factor" also has an oncogenic factor in patients' somatic cells. Under normal circumstances, this oncogenic factor is in an inactive state (inactive state), and it will not get sick under normal circumstances. However, under the influence of various internal and external environmental stimuli, the activity of this lipogenic factor is active and has certain activity. When the body's resistance decreases, the ability of immune cells such as lymphocytes and mononuclear phagocytes to monitor tumorigenic factors decreases. Under the induced conditions of internal environment changes, chronic inflammatory stimulation and abnormal body fat metabolism, the activity of lipogenic factors is further enhanced, and it combines with some gene fragments in normal cells of the body to form abnormal gene mutations. Lipoma is an abnormal proliferation phenomenon between normal lipoma cells and surrounding tissue cells, which leads to the deposition of adipose tissue and protrudes to the body surface or various internal organs. 1. People who drink too much and often eat fat meat, animal offal, scaleless fish or egg yolk. Because eating too many fatty products and foods with high cholesterol will lead to damp-heat in the spleen and stomach, endogenous phlegm-dampness, and imbalance of transport and transformation, that is, too much new adipose tissue will make too many fat cells in the body isomerize and harden. The treatment principle is: clearing away heat and removing dampness, invigorating spleen and regulating stomach, softening hard mass and resolving hard mass. Second, people with excessive work pressure, irritability and frequent anger. Due to stagnation of liver-qi, stagnation of qi and blood, and obstruction of meridians, normal adipose tissue can be intertwined with blood stasis, forming connective tissue to wrap adipose cells for a long time and forming lipoma. Treatment principle: soothing the liver and regulating qi, promoting blood circulation and removing blood stasis, softening and resolving hard mass. Through treatment, get through the channels and collaterals, dredge the menstrual blood and dissipate lipoma. Third, I often stay up late and miss too many people. Because the spleen and stomach are injured, the spleen loses its health, and the yin and yang are out of balance, so that the human body's ability to decompose fat is reduced, and the original adipose tissue and new adipose tissue can not be arranged normally, forming abnormal adipose tissue, that is, "lipoma." Treatment principle: invigorating qi and spleen, regulating the balance of yin and yang, softening and resolving hard mass. When editing the histopathological examination of this paragraph, except for the large mature fat cells, most of the proliferative blood vessels are visible in the tumor, and the whole tumor boundary is clear. Lipomas rarely become cancerous and generally do not need treatment; If the tumor is large, it affects the activity, or it suddenly increases or ruptures in the near future, it should be surgically removed. Lipoma mostly occurs under the skin, and there is a thin connective tissue envelope around the tumor, which contains normal fat cells divided into small Ye Qun by connective tissue bundles. Some lipomas contain not only a lot of adipose tissue, but also more connective tissue or blood vessels in structure, that is, complex lipomas are formed. According to the number of lipomas, this paragraph is divided into two types: single lipoma and multiple lipomas. This kind of tumor is common in shoulders, back, buttocks, limbs, waist, abdomen and inner thighs, and head diseases are also common. Lipomas located in subcutaneous tissue vary in size, most of which are oblate or lobulated with clear boundaries; People with unclear boundaries should beware of the possibility of malignant lipoma. A single lipoma is called solitary lipoma. Two or more are called multiple lipomas. According to different parts, it can be divided into subcutaneous lipoma and angiomyolipoma (also known as hook tumor). According to the location of lipoma, subcutaneous lipoma is a flat or lobulated, soft and well-defined local tumor at the lower limit of the skin. Soft, pushable, normal superficial skin, slow development, up to hundreds, often under the skin. Angiomyolipoma-Hamartoma is a lipoma (also known as renal hamartoma and hepatic hamartoma) located between the smooth muscle tissues of capillaries in various organs (kidney and liver are common). According to the different growth conditions of lipomas, they can be divided into three types and two stages, namely PNM classification. They divided lipomas into three types and two stages according to their clinical symptoms, course of disease, accompanying diseases, growth speed, shape, location, size and complications. The main significance of this classification method lies in different clinical types and stages, and it has its particularity in the treatment process. Only by accurately grasping the different types and stages of lipoma can we treat this disease more accurately and effectively and make the treatment more detailed. It is understood that most body surface tumors will not grow indefinitely, but some body surface tumors may change. How to judge their good or bad luck? Look at the growth rate of tumor: tumor cells tend to grow, while benign tumor cells grow slowly. Once the growth rate of tumor accelerates, it will be much larger than before in a short time, such as one or two months, two or three months, which may be a sign of malignancy. This growth rate has no absolute value, mainly compared with the last one. Lipoma-the shape of tumor on ——CT film: the shape of tumor is regular, the edge is clear, and most of them are benign; On the contrary, those with irregular shapes, unclear edges and uneven surfaces are mostly malignant. For example, whether the lump on the breast is lipoma or cancer, lipoma feels smooth and complete, and can be pushed without sticking to the skin. The surface of the tumor is not only like a burr, but also the lump sticks to the skin. Look at the hardness of the tumor: the harder the tumor is, the greater the possibility of malignancy. Look at the activity of tumor: Benign tumor has a large activity, that is, it is separated from surrounding tissues, such as lipoma, which is very soft and can be pushed by hand; However, malignant masses have little or no activity and attach to the skin and basal part. See if there is any ulceration on the surface of the tumor: if there is ulceration on the surface of the tumor, except tuberculosis or local infection, malignant tumor should be suspected. In comparison with the above methods, if in doubt, you should be vigilant. Lipoma is a metabolic disease of fat, so all fat-rich parts of the body are prone to lipoma. Among them, shoulder, back, upper arm, hip and knee joint are more common. Tumors usually vary in size, as small as soybeans and as large as more than 20 kilograms. The tumor develops slowly, is oblate, soft and elastic, with clear boundaries and normal skin color. If the hand is pressed tightly against the base of the tumor, due to the traction of the fiber bundle, the skin surface can be seen to shrink and sag, showing an "orange peel". There is also a lipoma, which is multiple and symmetrically distributed all over the body, but it is more common in the back and limbs. As small as a soybean, occasionally the fingertips are big, the edges are clear, and it can be pushed, and it is slightly adhered to the skin and tender. Lipoma is easily confused with what disease. Lipoma is very common and generally does not require treatment. But if other malignant tumors are misdiagnosed as lipomas, it will delay the illness and make a big mistake. Therefore, we should distinguish this disease from other similar tumors here: lipoma (sebaceous cyst) is a small tumor, mostly bean-shaped, round and soft, with cysts outside, and a filthy bean dregs-like substance flows out after it is broken, which smells bad. In addition, there was no long-term caking at the lesion site before the onset. Multiple neurofibroma has a wide tumor body, obvious finger pressure, special freckles and mental retardation. 1. The diagnosis of this disease is mainly based on symptoms and physical examination. Especially the surface features of tumors. 2. In order to distinguish it from other diseases, the examination items may include a check box "b". A: It is common in the neck, back, scapula and forearm, and can also occur in other parts of the body. B. it is more common in adults. C. most of them are multiple, and a few are single. Schematic diagram of lipoma D. The tumor is oblate or round, with clear boundary, unchanged skin color and soft texture. A few hard people feel no pain, but they have a false sense of fluctuation. Typically, the mass is pinched by hand, and the surface can be divided into leaves, and the mass grows slowly. Edit the diagnostic basis of this paragraph (1). It usually occurs in the neck, back, scapula and forearm, but also in other parts of the body. (2) More common in adults. (3) Most of them are single and a few are multiple. (4) Tumors vary in size, oblate or round, with unclear boundaries, unchanged skin color, soft texture, painless touch and the illusion of fluctuation. Typically, the tumor is squeezed tightly by hand, the surface may be lobulated, and the tumor grows slowly. Powder tumor, lipoma and neurofibroma are common benign tumors on the body surface. Powder tumor, also known as sebaceous cyst. Located in the dermis, it has a complete capsule, which contains tofu-like secretions and is accompanied by odor. Soybean is big, jujube is big or bigger. Face, behind the ears, back and buttocks are the most common parts. It is easy to get infected and fester in summer. Lipoma is located in subcutaneous adipose tissue and is formed by accumulation of mature adipose cells. Mostly in the trunk and upper limbs. There are many singles, ranging in size and some as big as fists. Oblate or round, lobulated, with a complete thin capsule. Soft texture, light yellow section. Neurofibroma is a dominant genetic disease with a family history. Nerve trunks or nerve endings originating from all parts of the body are located under the skin and have the characteristics of multiple occurrences. The tumor is small, pushable, tough, with clear boundaries and no capsule. The section is gray and translucent.