The skin color of the first vulva is mostly purplish red or reddish, and it can also be grayish white or grayish blue, which is mixed with well-defined white keratinized plaques with different shapes and sizes. Mixed malnutrition has mixed symptoms of atrophy and hyperplasia. The clinical manifestations of vulva leukoplakia include obvious atrophy of vulva, hypertrophy of clitoris prepuce, obvious keratinization, coarse lines of labia majora, hypopigmentation and localized thickening ulcer. The affected skin is rough, lichen-like, with scratches and sometimes chapped. Local hypopigmentation, labia majora and labia minora generally turned white. The vulva of the patient can be slightly atrophied. In severe cases, the clitoris, labia majora and labia majora are atrophied and adhered, and the labia minora partially or completely disappears. After that, the vagina mouth is narrow and the elasticity disappears, which even affects urination and sexual life. Systemic disease factors such as diabetes, jaundice, autoimmune diseases and metabolic dysfunction diseases. This is one of the symptoms of vulvar leukoplakia.

Second vulvar itching is the most prominent symptom of vulvar leukoplakia, especially at night. The degree of itching is related to time, menstruation, climate, food, environment and mood. Itching is usually intermittent, and patients often scratch and scratch because of strange itching. Due to scratching, the external vagina has many scratches and redness, which is the result of long-term itching, causing local collapse, chapping, ulceration and secondary infection. Therefore, patients often have local burning pain, especially clitoris and labia minora, which are very sensitive. The symptoms of vulvar leukoplakia are hyperkeratosis and infiltration of fat skin in the early stage. Localized or diffuse white thickening of vulva skin and mucosa, leather-like swelling, wrinkles, scales and eczema-like changes.