Table of Contents 1 Pinyin 2 English Reference 3 Overview 4 Pharmacopoeia Standard of Oil of Iodide 4.1 Name 4.1.1 Chinese Name 4.1.2 Chinese Pinyin 4.1.3 English Name 4.2 Source (Name), Content (Potency) 4.3 Characteristics 4.4 Identification 4.5 Inspection 4.5.1 Acidity 4.5.2 Color 4.5.3 Free Iodine 4.6 Determination of Content 4.7 Category 4.8 Storage 4.9 Preparation 4.10 Version 5 Iodized oil 5.1 Synonyms of iodized oil 5.2 Indications of iodized oil 5.3 Dosage and usage of iodized oil 5.4 Precautions 5.5 Specifications P.S. * Other versions of iodized oil 1 Pinyin

diǎn huà yóu

2 English Reference

iodized oil [21st Century Dictionary of Bilingual Science and Technology]

3 Overview

iodized oil is an iodine-containing plant that is used for the production of iodine and for the treatment of iodine. p> Iodized oil is the iodide of iodine combined with vegetable oil, colorless or light yellow, insoluble in water, can be dispersed and emulsified with water. Concentration of 40% of iodized oil, used for bronchography, fistulography, pus cavity imaging and hysterosalpingography. The emulsified iodized oil can be used as embolic agent for liver cancer. If the iodized oil has free sulfur branches and its color changes to brownish red, it cannot be used.

4 Iodinated Oil Pharmacopoeia standard 4.1 Name 4.1.1 Chinese name

Iodinated Oil

4.1.2 Chinese Pinyin

Dianhuayou

4.1.3 English name

Iodinated Oil

4.2 Source (name), content (potency)

The product is a kind of organic iodine compounds of vegetable oil and iodine combination. Compound. Iodine (I) should be 37.0% ~ 41.0% (g / g).

4.3 Properties

The product is a light yellow to yellow clarified oily liquid; slightly similar to the odor of garlic.

The product is soluble in acetone, trichloromethane, ether or petroleum ether, insoluble in water.

4.4 Identification

Take the product, small fire slowly heating, gradually show red to brown, and the occurrence of purple iodine vapor, can make the wet potassium iodide starch test paper blue.

4.5 Check 4.5.1 Acidity

Take 1.0g of this product, add 10ml of trichloromethane to dissolve, add 3 drops of phenolphthalein indicator solution with 0.30ml of sodium hydroxide titrant (0.1mol/L), it should show pink color.

4.5.2 Color

Take the product and compare it with the yellow No. 10 standard colorimetric solution (2010 version of the Pharmacopoeia, Part II, Appendix IX A, the first method), it should not be darker.

4.5.3 Free iodine

Take 1.0g of this product, add trichloromethane 5ml, shake well, add 10ml of water with potassium iodide 0.5g, dissolve, add starch indicator solution 1ml, shake, the aqueous layer, such as blue-purple color, add 0.1mol/L sodium thiosulfate solution 1 drop, the blue-purple color should disappear immediately.

4.6 Content determination

Take about 0.6g of this product, precision weighing, placed in an evaporating dish, add potassium hydroxide ethanol solution (1 → 10) 40ml, covered with a surface dish, placed on a water bath evaporation to the block, the surface dish washed with a small amount of water, the washings and into the evaporating dish, and continue to evaporate to nearly dry, with hot water 150-200ml will be washed into the residue of the stoppered conical flask, cooled, add ice acetic acid 5ml with eosinophilic acid. Glacial acetic acid 5ml and eosin sodium indicator solution 5 drops, titrate with silver nitrate titrant (0.1 mol / L) to red. Each 1ml of silver nitrate titrant (0.1mol/L) is equivalent to 12.69mg of I.

4.7 Category

Diagnostic drugs, iodine supplementation.

4.8 Storage

Sealed tightly and kept under shade.

4.9 Preparation

(1) Iodized oil soft capsule? (2) Oil iodide injection

4.10 Version

The Chinese People's **** and the National Pharmacopoeia 2010 Edition

5 Oil iodide instruction 5.1 Alias of oil iodide

Oil iodide ,iodized oil

5.2 Indications of oil iodide

Mainly used for bronchial and uterus, fallopian tubes, Loup tubes and other imaging, also used for the prevention of endemic goiter.

5.3 Dosage and usage of oil iodide

Contrast examination: direct introduction of catheter. Prevention of endemic goiter: mostly intramuscular injection, can also be taken orally intramuscular injection: preschool children a dose of 0.5 ml, school-age children and adults a dose of 1 ml, injection every 2 ~ 3 years. Oral: 0.2-0.3g per dose for preschool children, 0.4-0.6g per dose for school-aged children and adults, once every 1-2 years.

5.4 Precautions

1. Oil iodide injection is viscous, and a thicker needle should be used for injection. Iodine allergy is contraindicated.

2. It should be kept away from light.

3. Contraindicated in patients with hyperthyroidism, senile nodular goiter, thyroid tumor (cancer), fever, heart, liver, lung disease.

5.5 Specification