Disease analysis: Hello, aspartate aminotransferase, also known as aspartate aminotransferase, usually exists in mitochondria of myocardial cells and liver cells, with the highest content in cardiac myocytes, followed by liver cells. Aspartate aminotransferase is one of the liver function tests, which is generally used to test whether the liver tissue is damaged. Suggestions: Aspartate aminotransferase is an important item in liver function test, which can test whether liver tissue is damaged. Because aspartate aminotransferase exists in mitochondria of hepatocytes, serum aspartate aminotransferase will increase only when liver tissue is seriously damaged. In acute icteric hepatitis, chronic active hepatitis, severe hepatitis, liver cirrhosis and liver cancer, the serum aspartate aminotransferase will increase significantly.