At present, there are two kinds of drugs to treat obstetric cholestasis. The specialized treatment centers of obstetric cholestasis tend to use ursodeoxycholic acid, which can eliminate or alleviate itching symptoms and make liver function and cholic acid indexes return to normal. Hormone drugs (mainly dexamethasone) can also be considered for the treatment of obstetric cholestasis, but pregnant women should be closely observed when using them. At the same time, some topical antipruritic drugs can be used, such as calamine lotion.

Pregnant women with obstetric cholestasis may bleed after delivery. Because taking vitamin K from food requires bile, and vitamin K helps blood coagulation. Therefore, some hospitals will let expectant mothers take vitamin K orally every day until delivery to prevent them from bleeding, even if it is very dangerous, and the baby will be protected by vitamin K.

As far as infants are concerned, the main goal of treating obstetric cholestasis is to eliminate the possibility of death in the mother's stomach. When their lungs are mature enough to adapt to life outside the uterus, they should give birth as soon as possible Now doctors think it is best to give birth within 35 ~ 38 weeks of pregnancy. If pregnant women induce labor within this time range, the chances of the baby's survival are very high. If they wait until 40 weeks of pregnancy to give birth, the chances of the baby's fetus dying in the womb will increase.