The symptoms of thalassemia are manifested in many aspects, and most thalassemia patients get sick in infancy. At this time, the patient will have anemia, weakness, abdominal agglomeration, developmental retardation and so on. And severe patients will have growth retardation and die before adulthood.
Patients with mild illness can generally live to adulthood and participate in labor. If kidney essence is insufficient, it will also affect the acquired spleen and stomach function and growth and development. After a long time, blood gas deterioration, jaundice, accumulation and other manifestations will occur, which will lead to the greater harm of this syndrome of excess and deficiency to patients.
Extended data:
Characteristics of thalassemia patients:
1, HbA2 increased.
HbA2 in most thalassemia patients will increase, while HbF in severe β thalassemia usually increases, sometimes reaching 90%; The increase of HbA2 is usually above 3%.
The percentage of HbA2 and F in patients with α thalassemia syndrome is generally normal, which has become the main way to determine that people are thalassemia.
2. Osteoporosis
Patients with severe β -thalassemia will have the characteristics of chronic bone marrow hyperactivity, which is characterized by thinning of cortical layer of skull and long bone, widening of bone marrow cavity and obvious gap between skull plates, and sunlight in trabecular plates.
At this time, there may be osteoporosis areas in people's long bones, and people's cones and skulls may be granular or ground glass-like, reminding people to treat them in time after discovering these conditions.
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