About 429 kilometers. It takes about 4 hours and 29 minutes to drive from Changzhou to Xuzhou via Huaixu Expressway, Xinyang Expressway, Su Yang Expressway, Liyang Expressway and Hu Rong Expressway. The whole journey is about 429 kilometers. You can also drive through Luo Yan Expressway, Beijing-Shanghai Expressway and Jiang Yi Expressway. The whole journey is about 436 kilometers and takes about 4 hours and 40 minutes.