The five major harms of drugs are:

1. Drugs are easy to become addicted. Taking drugs can give people a sense of pleasure, which can easily make us physically and psychologically dependent on drugs, making us slaves to drugs.

2. Drugs harm families. Once one person in the family is addicted to drugs, a large amount of money will be spent to buy drugs, the family property may be sold or even loan sharking may be taken out, and the whole family's life will be uneasy.

3. Drugs can easily spread diseases. After becoming addicted to drugs, drug addicts generally lose interest and ability in work and life, and will do whatever it takes to obtain drugs. Many drug addicts take drugs through intravenous injection, and drug addicts generally have chaotic private lives, which can easily spread AIDS.

4. Drug abuse can easily lead to crime. After becoming addicted to drugs, in order to obtain money to buy drugs, drug addicts often take risks and engage in illegal and criminal activities, endangering the safety of others and the public order of society.

5. Drugs cause people to lose their personal self-esteem.