Transmission route: it is mainly transmitted by droplets in the digestive tract or respiratory tract, and it may also be infected by contact with herpes fluid of patients' skin and mucosa.
Main symptoms: fever symptoms first, maculopapules and herpes on palms and soles (redness around rash), herpes and/or ulcers on oral mucosa, and obvious pain. Some patients may be accompanied by cough, runny nose, loss of appetite, nausea, vomiting, headache and other symptoms. A few patients are seriously ill and may be complicated with encephalitis, meningitis, myocarditis and pneumonia.