9 years of history of diabetes, fasting blood glucose can be at the level of 7, 8mmol / L, it should be said that the fasting blood glucose is still relatively stable, so does it mean that the blood glucose control is relatively good?
In the treatment of diabetes, for the control of blood glucose requirements, we do not care to look at the fasting blood glucose, but also look at the postprandial blood glucose, and diabetic friends specific situation to determine whether the control is better.
Importance of stable blood glucoseFor diabetics, stable blood glucose is always a goal to be achieved. And stable blood sugar should not only look at the fasting blood sugar is stable, but also to test the postprandial blood sugar, preprandial, postprandial blood sugar difference of 3mmol / L or less, then it shows that the blood sugar control is relatively stable.
Stabilized blood glucose can reduce damage to the large blood vessels and microvessels, and reduce the occurrence of complications, and the variability of blood glucose is usually used to indicate whether the blood glucose control is stable or not.
Glycemic variability is a non-stationary state in which blood glucose levels vary between high and low fluctuations, persisting across the day and between days.
Glycemic variability has been demonstrated by a large number of studies to be significantly associated with the clinical prognosis of patients with diabetes mellitus, and the time in target range (TIR), one of the key metrics for assessing short-term glycemic variability in the CGM report, has been gaining clinical attention in recent years.
Series of studies have suggested that glycemic variability is an important indicator of the state of glycemic control in diabetes mellitus and has an important impact on glycemic management.
Increased glycemic variability can lead to oxidative stress, endothelial dysfunction, activation of the coagulation system and inflammatory response, and other adverse metabolic processes, which are involved in the development and progression of diabetic complications.
Glycated hemoglobin (HbA1c) is widely used as the "gold standard" for assessing glycemic control, but it still has limitations such as its inability to reflect the dynamic changes in blood glucose. The development of ambulatory glucose monitoring (CGM) technology has brought new opportunities for comprehensive assessment of patients' glycemic control.
Requirements for glycemic control in different conditionsFasting blood glucose is recommended to be below 7 mmol/L and postprandial blood glucose below 10 mmol/L for diabetic patients with a relatively short duration of illness and without various acute and chronic complications of diabetes, which is ideal for glycemic control.
For the longer course of the disease, combined with cardiovascular and cerebrovascular diseases, shorter life expectancy, mental anomalies and other conditions, fasting blood glucose control in the 8mmol / L, postprandial blood glucose of 12mmol / L or less glucose is also possible.
But for patients with diabetes in pregnancy or gestational diabetes, the fasting glucose control requirements for 3.3-5.1mmol/L, postprandial glucose 4.0-6.7mmol/L, so the fasting glucose for 7, 8mmol/L control level is still relatively poor, and need to be adjusted as soon as possible to ensure that the normal conduct of pregnancy.