Chemical peeling is to corrode and destroy the epidermis with high concentration of acidic chemicals to achieve the effect of peeling, thus removing wrinkles. There are many formulas for chemical peeling, but they can be roughly divided into two categories: one-time intense chemical peeling and repeated mild chemical peeling. Exfoliate the cutin of the superficial skin violently at one time. The patient needs hospitalization, anesthesia, great pain and long-term repair. If the drug penetrates too deeply due to improper operation, it will leave scars and pigmentation after healing. Moreover, improper medication through skin absorption will lead to systemic poisoning. Mild chemical peeling for many times adopts glycolic acid aqueous solution with the reputation of "the first fruit acid". A severe chemical stripping is divided into four steps: the patient does not need hospitalization, anesthesia, pain, work and work, systemic absorption poisoning and postoperative pigmentation. High concentration glycolic acid has certain curative effect and good safety, but it needs to be operated by trained professionals. Chemical peeling by this method is rare and takes a short time. How effective it is needs further observation.