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What are the treatments for uterine fibroids?

Uterine fibroids are mainly caused by the proliferation of immature uterine smooth muscle cells, so they are also called uterine leiomyomas. They are the most common tumors in the female pelvic cavity, accounting for 1 in 4 to 5 women over the age of 35. There is 1 patient with this disease. It is generally believed that the main cause of uterine fibroids is long-term and sustained stimulation of large amounts of estrogen, especially when only estrogen acts without progesterone. Most patients are asymptomatic and are only discovered during physical examination; however, submucosal fibroids or larger intramural fibroids may cause menorrhagia, prolonged menstruation or irregular bleeding. In severe cases, secondary anemia may occur. ; A few patients have abdominal pain and compression symptoms (such as difficulty defecating or urinating), as well as secondary infertility; a mass can be palpable in the lower abdomen during physical examination, and the uterus is enlarged, hard, and has an uneven surface. Clinically, fibroids are often divided into subserosal fibroids, intramural fibroids, submucosal fibroids, cervical fibroids, broad ligament fibroids, etc. according to their different growth locations. Detection of the uterine cavity can reveal growth or deformation, and B-mode ultrasonography can assist in diagnosis.

Non-surgical therapy and surgical therapy are used based on the patient's age, fertility status and clinical manifestations. Non-surgical treatment mainly uses uterine sphincter and androgens to treat patients with heavy menstrual flow and small fibroids. For patients with large fibroids and obvious symptoms who are ineffective in non-surgical treatment, surgical treatment can be used.

This disease generally belongs to the categories of syndromes such as "癓癕" and "heavy menstruation" in traditional Chinese medicine. Qi stagnation, blood stasis, and phlegm stasis are combined in the uterus, which is the basic cause and pathology. Blood stagnation and phlegm accumulation are often closely related to the invasion of external evils (such as dampness and heat) and the dysfunction of organ functions. In the later stages of the disease, the patient's vitality is often severely damaged (deficiency of qi and blood, imbalance of yin and yang), while phlegm and stasis remain. In the early stage, it is advisable to activate blood circulation and regulate qi, break up blood stasis and dissipate stagnation, clear away heat and eliminate phlegm. If the patient has excessive bleeding and serious damage to his qi, then he should use both attack and supplement, that is, when activating blood circulation and dispersing phlegm and softening hardness, he should use the appropriate method of nourishing qi, nourishing blood and replenishing phlegm. The essence of the product can eliminate evil without causing damage.

This excerpt introduces 13 effective prescriptions for the treatment of uterine fibroids, such as the Xiaoliu series and the enema Xiaohui prescription, which can be selected according to the clinical situation.

1. Composition of a series of anti-tumor prescriptions: ①Non-menstrual prescription: 9g each of angelica root, chuanxiong root, rehmannia root root, white peony root, peach kernel, safflower, trigonellae, zedoary zedoary, kelp, kelp, seaweed, salvia miltiorrhiza, and Liu 15g each of Jinu and Turtle Armor. ② Menstrual prescription: 9g each of Angelicae Sinensis, Rehmannia glutinosa, White Peony Root, Rubia Cortex, Puhuangtan, and Chuanxiong, 15g each of Salvia Miltiorrhizae and Lithospermum rhizome, and 12g each of Donkey-hide Gelatin and Motherwort.

Additional and subtractive changes: If there is weakness of Qi and blood, add astragalus, dangshen, etc. to the above two prescriptions; if there is obvious dampness and heat, add coptis, baicalensis, etc.; if the blood heat is severe, add gardenia, paeonol, etc.; For patients with liver stagnation or premenstrual breast bloating or lower abdominal distension, add Bupleurum, Yujin, etc.

Treatment methods: Take 1 dose a day during non-menstrual periods and during menstruation. Take it.

Effects: Promoting blood circulation and removing blood stasis.

Clinical application: 42 cases were cured, accounting for 21.4%. , all were single small fibroids. 17 cases were effective, accounting for 42.8%, including 12 cases of single fibroids and 5 cases of multiple fibroids, 7 cases were effective, accounting for 16.6%, including 5 cases of single fibroids and multiple fibroids. There were 2 cases of uterine fibroids. There were 9 cases of ineffectiveness, accounting for 21.4%, of which 5 cases were multiple fibroids. The total effective rate was 78.5%.

Experience shows that uterine fibroids are common benign diseases in gynecology. Tumors have a high incidence, and modern medicine mostly uses surgery to treat uterine fibroids. It has been found that conservative treatment of uterine fibroids can also achieve satisfactory results.

The source of the prescription is Liu Ying, et al. Summary of the clinical treatment of 42 cases of tumor. Tianjin Traditional Chinese Medicine, 1989, (5): 16.2. The drug composition of enema Xiaohui prescription is peach kernel, Chuanxiong, Trigonella, Curcuma, pangolin, Akebia, Passepartout, tangerine peel, Citrus aurantium, Laminaria , 15g each of oysters, and 12g worms.

Additional changes: Add 15g of Prunella Vulgaris and Pinellia ternata for those who are obese and have excessive phlegm and dampness.

Treatment method: Decoct in water and extract the juice. to 100ml, and the temperature is around 40℃ (it is better to drop it on the forearm without being hot or cold). Empty the stool before enema, insert a medium-sized urinary catheter 15-20cm into the anus, and slowly inject the liquid into the rectum with a 100ml syringe. After pulling out, raise the breech position, lie on the left side, and keep it for 2 hours. One course of treatment is 30 times a day, and the enema should be stopped for 1 to 4 consecutive courses. Due to discomfort in the early stage, the urge to defecate may occur immediately after enema, which will gradually disappear after several times. During the treatment, symptoms such as slight pain in the lower abdomen may occur, indicating that the drug has reached the disease site and the treatment effect is good.

After each course of treatment, a gynecological examination and B-ultrasound review are performed, usually 3 to 7 days after menstruation.

At the same time, it is combined with traditional Chinese medicine syndrome differentiation and oral administration of traditional Chinese medicine. For spleen and kidney yang deficiency type (early menstruation, heavy menstruation or continuous dripping, light red color, pale or swollen complexion, fatigue, excessive leucorrhea, pale tongue, etc.) use 15g each of Codonopsis pilosula, Astragalus membranaceus, Chinese yam, Rehmannia glutinosa, and Poria cocos. , 9g each of Atractylodes macrocephala, Chuanduan, Morinda officinalis, 7g tangerine peel, 20g Millet Spatholobus; for qi stagnation and blood stasis type (heavy menstrual flow or irregular bleeding, dark red color or blood clots, lower abdominal distension and pain, etc.) use Angelica sinensis. , Chuanxiong rhizome, red peony root, 9g each of safflower and tangerine peel, 10g each of Salvia miltiorrhiza and Achyranthes bidentata, 12g peach kernels, 15g each of toochean root, cyperus rotundus and adipose root; liver and kidney yin deficiency type (early menstruation, heavy amount, red color Thick, flushed cheeks, hot palms and soles, dizziness, tinnitus, soreness and weakness in the waist and knees, etc.) Use 15g each of raw and cooked rehmannia, yam, cornus, wolfberry, Achyranthes bidentata, calcined dragonfly, and prunella vulgaris, Ligustrum lucidum, white 12g each of peony root, 9g each of paeonol bark and tangerine peel. The above prescriptions are all decocted in water and taken orally, one dose per day, and the course of treatment is the same as that of Guantang Xiaohui Prescription.

Effects: Invigorating blood circulation and removing blood stasis, eliminating addiction and softening hardness. Mainly treats uterine fibroids.

Clinical application: There were 54 cases in this group, all of which were patients who were unwilling to undergo surgical treatment. After combined internal and external treatment with the above method, the results: improvement of clinical symptoms: among 27 cases of irregular menstruation, 13 cases were cured after treatment, 11 cases were markedly effective, 2 cases were effective, and 1 case was ineffective. The total effective rate was 96.3%; other symptoms The improvement efficiency is 100%. Changes in fibroid volume: 30 cases were cured after treatment, 10 cases were markedly effective, 6 cases were effective, and 8 cases were ineffective. The total effective rate was 85.2%.

Experienced experience shows that this prescription can regulate qi and activate blood circulation, soften hard clumps, dry dampness and eliminate phlegm. It can be combined with syndrome differentiation and use oral prescriptions, internal and external treatment, both attack and tonic, and long-term use, so the curative effect is very significant. .

The uterus is located in the lower abdomen. Due to the thin walls of the pelvic veins, lack of sheaths, lack of valves in small and medium-sized veins, and numerous venous plexuses, the venous system of the pelvic organs is like a swamp connected by a water network. Moreover, the rectal and uterovaginal veins anastomose with each other. Therefore, it is assumed that drugs absorbed through the rectum can quickly diffuse in the pelvic cavity, allowing them to reach the diseased uterus directly, maintaining the local effective concentration of the drug within a certain period of time, and avoiding gastrointestinal irritation of the products that break the strong and fight blood stasis.

The source of the prescription is Zhang Jie, et al. Clinical observation on 54 cases of uterine fibroids treated with traditional Chinese medicine enema. Journal of Traditional Chinese Medicine, 1991, (10): 44.3. The drug composition of Shenqi Longmu Decoction is 10g each of Codonopsis pilosula, Atractylodes macrocephala, Schisandra chinensis, Cortex chinensis, turtle shell, and Scutellaria baicalensis, 12g each of Astragalus membranaceus and Gallus gallus gallus L., 20g each of raw keel bone, calcined oyster, and Polygonum multiflorum, and 15g Scrophulariaceae.

Treatment method: For early menstruation, add Erzhi Pills; for those with excessive bleeding, add Gorgon Fruit and Sea Turtle; for dysmenorrhea, add Shaoyao Licorice Decoction or Shi Xiao Powder. One dose per day, 3 months as a course of treatment. During the treatment period, other Chinese and Western medicines are discontinued.

Effects: Replenishing qi and nourishing yin, softening and dispersing stagnation. Mainly treats uterine fibroids.

Clinical application of 58 patients after 1 to 2 courses of treatment, various symptoms were improved to varying degrees. Among them, 39 cases had heavy menstrual flow, and 35 cases had reduced menstrual flow after treatment, accounting for 89.7%; 20 cases had early menstruation, and 17 cases had returned to normal after treatment, accounting for 85%; 9 cases had prolonged menstruation, and 7 cases had improved, accounting for 85%. 77.8%; 8 cases had dysmenorrhea, 5 cases improved, accounting for 62.5%; 36 cases had abdominal distension and low back pain, 26 cases improved, accounting for 72.2%; 2 cases had primary infertility, 1 case was pregnant. Dizziness, fatigue, anemia and other symptoms were significantly improved. According to B-ultrasound, the fibroids disappeared or the total area was reduced by about 1/2 in 28 cases, reduced by 1/3 in 19 cases, and ineffective in 11 cases.

Experienced experience shows that this disease occurs more often in new births, careless menstruation, cold evil that makes it difficult to weep, or heat that boils into lumps, or qi stagnation for a long time, resulting in blood accumulation in the abdomen due to qi and blood. Clumped. Only by replenishing qi and nourishing yin, softening and firming astringent, can we achieve better curative effect. In particular, the efficacy is better for intramural patients, but worse for subserosal and submucosal patients. In addition, after taking this prescription, it was found that it has an effect on myonuclei of different sizes. It is speculated that its mechanism of action may be related to the adjustment of the endocrine function in the body, thereby inhibiting the growth of fibroids and causing them to gradually shrink.

The source of the prescription is Ye Qing, et al. 58 cases of uterine fibroids treated with Shenqi Longmu Decoction. Shandong Journal of Traditional Chinese Medicine, 1988, (4): 24.4. The drug composition of Guijia Gongai Decoction is 12g each of Angelicae Sinensis, Paoshan Jia, peach kernel, Curcuma Curcuma, Cyperus rotundus, Dipsacus Dipsacus, Prunella Vulgaris, and Achyranthes bidentata, 9g each of Wangbuliuxing and Trigonellae, 15g of Laminaria, and 30g of Yiren.

Treatment methods: add Codonopsis pilosula or Radix Pseudostellariae for qi deficiency; add Spatholobus and white peony root for blood deficiency; add Zishu and Poria cocos for spleen deficiency; add wolfberry, mulberry, and Eclipta grass for liver and kidney yin deficiency. At the beginning of menstruation, add 4ml of 300% Sanleng Injection intramuscularly once a day. Use it for 7 days.

Effects: Indications: activating blood circulation and removing blood stasis, softening and dispersing stagnation. Mainly treats uterine fibroids.

Clinically applied in this group of 136 cases, 72 cases were cured (symptoms disappeared, tumors dissipated, and the uterus returned to normal size), accounting for 52.9%; 37 cases were markedly effective (symptoms basically disappeared, tumors were significantly reduced), accounting for 52.9%. 27.2%; effective (symptoms improved significantly, but tumor shrinkage was not obvious or not reduced) in 5 cases, accounting for 3.7%; ineffective (symptoms and signs did not improve) in 22 cases, accounting for 16.2%. The total effective rate is 83.8%.

Traditional Chinese medicine believes that this disease is often caused by empty cell veins after childbirth or open blood chambers during menstruation. Evil Qi takes advantage of the deficiency and invades, causing Qi and blood stagnation; or anger damages the liver and Qi reverses the blood; or worry damages the spleen. , blood deficiency and qi stagnation, etc., all lead to blood stasis and stagnation, which gradually accumulates into boils. Symptoms include menstrual period, lower abdominal pain that refuses to be pressed, or lumps that are firm and unmovable. When examining the cause and treating the disease, attack should be the main focus. Depending on the rise and fall of the righteousness, both attack and supplement can be applied. Attack should be combined with supplement, or supplement should be combined with attack. The treatment principles are mainly to promote qi and break blood, soften hardness and eliminate accumulation, or supplement it with supporting the spleen, tonifying the kidney, and regulating the liver, so as to achieve the purpose of eliminating phlegm and dissipating stagnation.

Based on the analysis of this group of cases, the efficacy is related to the size and type of the tumor. Smaller tumors have higher efficacy, and intramural fibroids have better efficacy than subserosal fibroids. Therefore, surgical treatment is still appropriate for giant tumors and adenomyosis.

The source of the prescription is Wu Dingyan. Observation on the efficacy of Gonghuang decoction in treating uterine fibroids in 136 cases. Journal of Traditional Chinese Medicine, 1981, (1): 34.5. The ingredients of the modified Gongjian decoction are 100g of Wangbuliuxing, 30g each of Prunella vulgaris, raw oyster, and perilla.

Additional and subtractive changes: If the emphasis is on spleen and kidney qi deficiency, soreness in the waist and knees, and significant increase in leucorrhea, add 30g of raw yam, 18g each of jellyfish and zizhu, 10g each of red peony root and antler cream, and madder 9g; For those with deficiency of qi and blood, constant menstruation, and increased fatigue, add 30g of astragalus, 18g each of Atractylodes and Atractylodes, 15g rehmannia root, 10g each of angelica and white peony root, and 9g madder; more emphasis is placed on blood stasis in the uterus and lower abdomen For those who are stinging and refuse to press, add 10g peach kernel, 12g red peony root, 9g each of paeonol bark, poria, cassia twig, and 6g leech; for those with cold and pain in the lower abdomen, add Guangui and Paojiang each. 6g, 10g each of cumin, Wulingzhi and Puhuang, 12g each of Angelica sinensis and red peony root; for patients with qi stagnation in the veins and indistinct pain, add 7g Bupleurum, 10g each of Angelica sinensis, Atractylodes, red peony root and litchi core, and 6g Curcuma. .

The treatment method is to decoct the medicine and take it once a day or every other day. 30 doses constitute a course of treatment.

Effects: It mainly regulates menstruation and blood stasis, softens hardness and dissipates stagnation, lowers qi and resolves phlegm. Mainly treats uterine fibroids.

Clinical application of 10 cases of uterine fibroids in this group. After treatment with Gongjian Decoction, all subjective symptoms disappeared. Among them, 6 cases were reviewed by B-ultrasound and the sound image of the uterus was normal; 4 cases were reviewed by gynecology and the uterus returned to normal size.

Experienced Chinese medicine believes that blood stasis, qi stagnation and blood stasis, qi deficiency and blood stasis are the main causes of uterine fibroids. The key medicine of Wangbuliu in Gongjian decoction enters the liver and stomach meridian, reduces swelling and relieves pain, has special effects on promoting diuresis, enters the blood system, stimulates menstruation and dissipates stagnation, removes blood stasis and eliminates mass; Prunella vulgaris alone enters Jueyin to eliminate scrofula knots. Qi: Suzi is a good medicine for relieving qi and dispersing qi. The combined use of various medicines can stimulate menstruation and remove blood stasis, soften hardness and dissipate stagnation, reduce qi and resolve phlegm, and then distinguish the deficiency and excess of cold and heat in the internal organs and meridians, and then combine them with corresponding prescriptions, so it has a good effect on uterine fibroids.

The source of the prescription is Ban Xusheng. Gongjian decoction is modified to treat uterine fibroids. New Chinese Medicine, 1990, (1): 34.6. The drug composition of Quyu Xiaohui Decoction is 10g each of Angelicae Sinensis, Peach Kernel, Sanleng, and Cyperus rotunda, 12g each of Wangbuliuxing and Curcuma Curcuma, 15g each of Prunella Vulgaris, Shengguanzhong, Tiankuizi, and Sichuan Duan, and 20g each of raw oyster and seaweed. , kelp 30g.

Additional and subtractive changes: For those with weak Qi and blood, such as fatigue, palpitations, and shortness of breath, add 20g of Codonopsis pilosula and 30g of Astragalus membranaceus; for those with soreness and weakness in waist and legs, dizziness and tinnitus, add 12g each of Ligustrum lucidum and Eucommia ulmoides, and 20g Eclipta herb; If the vaginal discharge is usually heavy and yellowish and smelly, add 30g of Yiren and take a sitz bath with a product that can remove dampness and clear away heat.

Treatment method: decoction in water, 1 dose per day. If the patient is constantly dripping with menstrual fluid, use Shenghua Decoction plus 20g each of keel bone, oyster, and sea octopus, 30g Fulong liver, and 3g Panax notoginseng powder (flush) to temporarily treat the symptoms.

Effects: It mainly treats blood stasis and phlegm. Mainly treats uterine fibroids.

45 cases of clinical application of *** were observed.

Among them, 19 cases (42.2%) were cured (symptoms disappeared, tumors dissipated, and the uterus returned to normal), 13 cases (28.9%) were markedly effective (symptoms basically disappeared, and tumors shrank by 2/3), and effective (symptoms were significantly improved). , but the tumor shrinkage was not obvious) in 11 cases (accounting for 24.4%), and 2 cases (accounting for 4.5%) were ineffective. The overall effectiveness rate is 95.5%. The patients in this group took the most medications, 123 doses, and the least, 25 doses.

Empirical experience shows that uterine fibroids are common benign tumors in gynecology. They belong to the category of "癓癕" in traditional Chinese medicine and are difficult to treat. In this prescription, Sanleng and Curcuma zedoary are blood-stimulating products, which can activate the accumulation of menstrual blood, causing it to boil into blood stasis and stop the blood in the uterus; Guanzhong and mallow seeds can not only break blood stasis and eliminate abdominal pain, but also treat metrorrhagia; Laminaria , 'Seaweed, Prunella vulgaris, Wangbuliuxing, activating blood circulation and regulating menstruation as an auxiliary; supplemented with Cyperus rotunda to relieve depression and regulate menstruation, and tonify the liver and kidneys to stop metrorrhagia. Uterine fibroids are a chronic disease with a long course and slow onset of effects. Treatment should be continued over a long period of time and should not be given up halfway.

The source of the prescription is Zhao Shuying. Clinical analysis of 45 cases of uterine fibroids treated with traditional Chinese medicine. Tianjin Traditional Chinese Medicine, 1989, (3): 3.7. The drug composition of Huoxue Ruanjian Decoction is 30g of salvia miltiorrhiza, 20g of adenophora leaf, 12g each of angelica, chuanxiong, white peony root (or red peony root), and 10g each of trigonellae and zedoary.

Additional and subtractive changes: For qi deficiency, add Sijunzi Decoction; for menstrual period, add white peony root, agrimony, and moxa leaf charcoal; for kidney deficiency, add Dipsacus Dipsacus and Sangji.

The treatment method is to decoct the medicine in water and take it twice, one dose per day. Most medications take effect in about 3 months.

Efficacy: It mainly treats blood stasis and dissipates stagnation, nourishes blood and regulates menstruation. Mainly treats uterine fibroids.

In this group of 30 cases, 5 cases were cured, 6 cases were markedly effective, 10 cases were effective, and the total effective rate was 70%. For example, a 52-year-old worker has been experiencing heavy menstrual flow for 2 years. The uterus appears to be 2 months pregnant, hard, and uneven in surface. The A-ultrasound and menstrual curettage and pathological examination are used to diagnose uterine fibroids, but surgery cannot be performed because of high blood pressure. Conservative treatment with Western medicine is ineffective. Symptoms include dizziness and fatigue, less sleep and more dreams, and low back pain. Use the basic prescription plus Dipsacus and Parasitism. After taking the medicine for 3 months, the menstrual flow decreased, and the gynecological examination and A-ultrasound examination showed that the uterus was normal.

Experience ① Traditional Chinese medicine can reduce menstrual flow and improve symptoms in most patients. In some cases, the fibroids shrink after treatment, and in a few cases the uterus can return to normal. ② The method of traditional Chinese medicine is simple, has no obvious side effects, and does not require complicated equipment. It is especially suitable for conservative treatment with traditional Chinese medicine for young people who need to preserve the uterus, or for those with other diseases that contraindicate surgery. However, judging from the efficacy of this group of cases, the effect is better if the uterus is as large as about 2 months pregnant. For those with larger submucosal fibroids and uterine fibroids, the effect of traditional Chinese medicine treatment is unsatisfactory, and surgery is still appropriate. ③ Most of the effective cases in this group began to reduce their menstrual flow within 3 months of taking the medicine. Therefore, if the symptoms do not improve after more than 3 months of treatment with traditional Chinese medicine, the reasons should be analyzed and the treatment plan should be reconsidered.

The source of the prescription is Zhang Chuanfang, et al. Clinical observation on 30 cases of uterine fibroids treated with traditional Chinese medicine. Hubei Journal of Traditional Chinese Medicine, 1986, (4): 17.8. The medicine of Huayu Sanjie Decoction consists of 15g each of peach kernel and leech, 12g of rhubarb, and 20g each of raw oyster, turtle shell, turtle shell, cat's claw, prunella vulgaris, kelp, and seaweed.

Additional and subtractive changes: For severe blood stasis, add 12g each of Trigonella striata and Curcuma zedoaria; for patients with qi stagnation, add 10g each of Wuyao and Cyperus rotunda; for obvious qi deficiency, add 15g each of Codonopsis pilosula and Astragalus membranaceus; Yes For phlegm-dampness, add 15g each of Elephant Shell, Alisma, and Plantago Seed.

Treatment method: 1 dose per day, decoction in water. Start taking the medicine after menstruation and stop taking it during menstruation. In addition, you can use 100g each of rhubarb and Glauber's salt, 200g Cyperus rotunda, mix with an appropriate amount of rice vinegar, stir-fry and apply externally to the lower abdomen, once a day.

Efficacy: This prescription is mainly used to promote blood circulation and remove blood stasis, soften and disperse stagnation. Mainly treats uterine fibroids.

Clinical application: This prescription was used to treat 98 cases of uterine fibroids. All cases were confirmed by gynecological examination and B-mode ultrasonography. Results: 64 cases were cured (menstruation was normal, the amount was medium, the uterus returned to normal size by gynecological examination and B-ultrasound, the fibroids disappeared, and there was no recurrence within 1 year); 28 cases showed significant effects (menstruation was regular, the amount was average or slightly more, gynecological examination and B-ultrasound examination Ultrasound examination showed that the uterus was significantly smaller than before taking the medicine, and the fibroids shrank); 6 cases were ineffective. The overall effectiveness rate is 94%. And 5 people have become pregnant. Most menopause can be induced after taking the medicine. Recovered cases took a maximum of 160 doses, a minimum of 12 doses, and an average of 80 doses.

Experience and experience Judging from the treatment results, the curative effect of this group of patients in the age group over 46 years old is relatively satisfactory. After treatment, when menstruation becomes normal and the uterus returns to normal size, most patients will experience menopause.

In the 36 to 45-year-old age group, due to the long course of the disease, large, hard, and immobile uterus, the curative effect is not ideal (all 6 ineffective cases were treated with Western medicine surgery). Patients under the age of 35 can be cured if detected early and the disease course is short. In recent years, most reports on the treatment of this disease are about 85% effective, and the effective rate in this group of cases is 94%. This is inseparable from the early detection and early treatment of the disease, but the use of leeches, turtle shells, turtle shells and other flesh-and-blood drugs It is one of the important reasons for promoting blood circulation and nourishing yin to improve the patient's physical condition and promote disease recovery.

The source of the prescription is Wang Yugui, et al. Observation on the efficacy of Huayu Sanjie Decoction in the treatment of uterine fibroids in 98 cases. Zhejiang Journal of Traditional Chinese Medicine, 1990, (2): 69.9. Kunzao Ruanjian Powder consists of 30g each of kelp, seaweed, sea pumice (beaten, fry first), raw oysters (beaten, fry first), and 15g each of mountain arrowroot mushroom and prunella vulgaris.

Additional and subtractive changes: For patients with waist and abdominal pain, add 12g of Puhuang, 10g of fried Wulingzhi, and 15g of Yuanhu; for those with severe weakness of Qi and blood and moderate anemia, add 30g of Codonopsis pilosula and Astragalus membranaceus, and 12g of donkey-hide gelatin (Yang ); For those with excessive menstrual bleeding (the hemoglobin drops by more than 0.5g after each menstrual period), add 6g of Panax notoginseng powder (consumption), 30g of stamen stone (beat, decoct first), and 10g of Cimicifuga.

Treatment method: Take decocted in water, 1 dose per day, once in the morning and once in the evening, 20 days as a course of treatment. It requires 3 to 6 courses of treatment.

Efficacy: This prescription can soften hardness and disperse stagnation, detoxify and activate blood circulation. Mainly treats uterine fibroids.

Clinical Application This group of 30 cases were all outpatients, with the youngest age being 33 years old and the oldest being 50 years old. They showed symptoms of menstrual irregularities, shortened cycles, increased menstrual flow, general fatigue, etc.; the minimum course of the disease was 2 years, and the maximum duration was 2 years. It lasts 15 years; the smallest tumor is 6 weeks of gestation, and the largest is 14 weeks of gestation. After using the above treatment, the results were: 7 cases were markedly effective, 21 cases were effective, and 2 cases were ineffective (one case was diagnosed as uterine fibroadenoma by B-ultrasound examination, and the other case did not insist on taking the medicine).

Experience and experience: This prescription is an agreed prescription formulated by the Qingdao Institute of Medical Sciences. Through clinical observation of 30 cases, the results show that Kunzao Ruanjian Powder does have a good effect in relieving the clinical symptoms of uterine fibroids.

The source of the prescription is Li Weifen, etc. 40 cases of uterine fibroids treated by softening and dispersing knots. Journal of Traditional Chinese Medicine, 1992, (5); 45.10. The drug composition of the modified Guiling Pills is 10g each of cinnamon twig, poria, peach kernel, paeonol bark, red peony root, turtle shell, selaginella, qijia moxa, green bark, chuandan, and astragalus, 30g raw oyster, and 6g phellodendron.

Treatment method: Grind the medicine into fine powder and make pills with honey. Each pill weighs 10g. Take 3 times a day, 1 pill each time, and take it continuously for 1.5 to 3 months as a course of treatment. Stop taking medication during menstrual period. Check after each course of treatment. If normal, stop taking the drug. If not, continue with the second course of treatment.

Efficacy: This prescription is mainly used to promote blood circulation, remove blood stasis and eliminate mass. Mainly treats uterine fibroids.

Clinical application of this group of 60 cases of uterine fibroids, after 1 to 3 courses of treatment, the effective rate reached 100%, of which 43 cases were cured, accounting for 71.7%. For example, a 43-year-old teacher went to see a doctor because his menstruation was 10 days early and heavy. Pregnancy 5 and 3, gynecological examination: The uterus is enlarged to the size of a 40-day pregnancy, and is hard, and the right ovary is as big as an egg; Ultrasound examination: the anteroposterior diameter of the uterus is 6cm, the waves are reduced, needle-shaped, and the wave pattern is slow. The right ovary is 4×5×3cm. . Western medicine diagnosed uterine fibroids combined with right ovarian cyst. He complained of dizziness and weakness in his limbs. His tongue was pale and the coating was thin and white, and his pulse was stringy and weak. This is caused by weakness of Qi and blood, blood stasis and stagnation of Qi, leading to phlegm. After taking Guiling Pills for one course of treatment, the amount of menstruation was reduced and the spirit improved. After another course of treatment, the patient was reexamined 1 year and 7 months later. The gynecological examination and ultrasound were normal.

Experience and experience According to the pharmacological effects of modern medicine, this prescription has: ① By improving blood circulation, enhancing the adsorption function of the reticuloendothelial system and the phagocytic ability of white blood cells, promoting the absorption of inflammatory exudates; promoting hematoma The dissipation and absorption of masses thus play the role of anti-inflammation, swelling, and phlegm and accumulation. ② By regulating the contraction function of uterine smooth muscle, it promotes the complete discharge of decidua, stagnant blood and other residual tissues, thereby regulating menstruation, stopping bleeding and relieving pain. Therefore, this prescription is not only effective for uterine fibroids. It can also be used for diseases such as cervicitis, adnexitis and ovarian cysts. Guiling Pills is suitable for treating uterine fibroids for those with blood stasis, coldness and weakness, but less effective for those with yin deficiency.

The source of the prescription is Huang Chunduan. Summary of 60 cases of uterine fibroids treated with "Guiling Pills". New Chinese Medicine, 1982, (10): 24.11. The drug composition of Yiqi Xiaoliu Pill is 50g each of raw astragalus and vinegar wheat, 30g angelica, 25g each paeonol, red peony root, and seaweed, 20g each cinnamon twig, kelp, peach kernel, and rhubarb, and 15g each of mountain beetle, Fritillary fritillary, and licorice. .

Additional and subtractive changes: For patients with qi deficiency, add ginseng and yam; for patients with severe blood deficiency, add donkey hide gelatin; for patients with excessive menstruation, add motherwort; for patients with anorexia, add Neijin; for patients with severe abdominal pain, add Wulingzhi; for liver stagnation, add Wulingzhi For those with heavy bleeding, add Bupleurum and Turmeric; for those with heavy bleeding, add Panax notoginseng powder and Dichuan charcoal.

Treatment method: Grind the medicine into fine powder, refine the honey into pills, as big as mung beans, take 30g in the morning and evening.

Effects: Invigorating Qi and promoting blood, dispersing blood stasis and dredging collaterals, reducing swelling and relieving pain. Mainly treats uterine fibroids.

Clinical application This prescription was used to treat 93 cases of uterine fibroids, and 42 cases were cured, accounting for 45.29,6; 47 cases were improved, accounting for 50.5%, and the total effective rate was 95.8%. It was observed during treatment that no case had any side effects, and no case developed or worsened. For example, a 35-year-old teacher suffered from irregular vaginal bleeding for 2 months, continuous dripping, heavy menstruation, dark red color with lumps, abdominal distension and pain, shortness of breath, fatigue, poor appetite, pale tongue, white coating, and heavy pulse. Gynecological examination: The uterus is enlarged, and a 4×5cm2 mass and hard mass can be touched on the front wall of the uterus. B-ultrasound examination revealed a 5×5cm2 nodule shadow in the uterine cavity with unclear edges, suggesting uterine fibroids. This is Qi Jie (blood stasis type), and the treatment is suitable for replenishing qi and removing blood stasis, unblocking meridians and dispersing stagnation. Add 15g of donkey-hide gelatin and 12g of Panax notoginseng powder (infused) into Chuxiaoliu Pills, 2 times a day, take the medicine for 2 days, and the bleeding will stop. She was advised to take Xiaoliu Pills, add 30g of Gallus gallus gallus gallus gallus gallus gallus gallus gallus gallinae, grind it into powder and drink it. All the symptoms disappeared after 22 days of treatment. After gynecological examination and B-ultrasound, it was confirmed that the mass disappeared and the uterus was normal.

Experience ① From the perspective of traditional Chinese medicine, uterine fibroids are more common due to qi stagnation and blood stagnation. Treatment is mostly based on promoting blood circulation, removing blood stasis and dispersing stagnation. The author realized during the treatment that when removing blood stasis and dissipating stagnation, we should protect the healthy qi so that the blood stasis can be removed without damaging the body. Only by tonifying the internal organs and tonifying the internal organs and attacking appropriately can we obtain good results. ② In the prescription, astragalus and angelica replenish qi and blood, activate blood circulation and remove blood stasis; kelp and seaweed soften hard knots and eliminate phlegm; peach kernel, chuanjia, and red peony root activate blood circulation and remove blood stasis, reduce swelling and relieve pain; rhubarb purges fire and detoxifies, and removes visible stagnation; vinegar Wheat and cinnamon twigs replenish qi, nourish the heart and tonify yang; licorice harmonizes the medicinal properties. The combination of various medicines can invigorate qi and generate blood, dissipate blood stasis and unblock meridians, reduce swelling and relieve pain, and the medicines and symptoms are in harmony, so the curative effect is satisfactory.

Source of prescription Wang Mingyi, et al. Clinical observation on 93 cases of uterine fibroids treated with Xiaoliu Pills. New Chinese Medicine, 1992, (2): 40.12. Guiling Xiaoliu Pills consist of 12g each of cassia twig, turtle shell, and red peony root, and 15g of poria. 10g each of paeonol bark, peach kernel and pangolin.

Treatment method: Grind the above medicines into fine powder and refine the honey into pills. Each pill weighs 10g. Take 2 pills a day, 1 pill in the morning and evening. Taking it continuously for 1 month constitutes a course of treatment. Stop taking the medicine when menstruation occurs.

Effects: Invigorate blood circulation and remove blood stasis, eliminate hardness and dissipate stagnation, nourish blood and heat, regulate Chong and Ren, and nourish the middle and replenish qi. Mainly treats uterine tumors.

Thirty patients in clinical application were aged 40 to 50 years old. The proportion of uterine enlargement ranges from a minimum of 6 weeks of pregnancy to a maximum of 12 weeks of pregnancy. Treatment results: 18 cases were cured, 5 cases were markedly effective, 5 cases were effective, and 2 cases were ineffective. The total effective rate reaches 93.3%.

Experience and experience: 30 patients who were diagnosed with uterine fibroids through gynecological examination or diagnostic dilation and curettage pathology report were treated with Guiling Xiaoliu Pills and achieved good results.

The source of the prescription is Peng Huali. Guiling Xiaoliu Pills for the treatment of 30 cases of uterine fibroids. Beijing Traditional Chinese Medicine, 1989, (6): 3013. The drug composition of Juli Sanjie Pill is 60g each of orange core, litchi core, Polygonum multiflorum, motherwort, raw oyster and seaweed, 30g each of Dipsacus scutellariae and Codonopsis pilosula, fennel, Wuyao, Melia azadirachta, Curcuma zedoary, Gangmin root, 10g each of chestnut shells.

The treatment method is to take the medicine as a pill, 3 times a day, 6g each time, take it with boiled water when half hungry and half full. If the body is hot or has both symptoms of heat, take it with light salt water. Start taking it 3 days after menstruation, stop taking it 3 to 5 days before menstruation, take 3 months as a course of treatment, and observe 1 to 3 courses.

Efficacy: It mainly treats qi and dissipates stagnation, softens hardness and restrains astringency, replenishes qi and activates blood circulation. Mainly treats uterine fibroids.

Clinical application of Juli Sanjie Pills in the treatment of 150 cases of uterine fibroids, 18 cases were cured, accounting for 12%; 111 cases were effective, accounting for 66.1%; the total effective rate was 86%.

Experienced pharmacological experiments of Juhe Sanjie Pills have shown that: ① This prescription can reduce estrogen levels and inhibit isolated uterine smooth muscle. It is of certain significance in reducing uterine bleeding and the gradual shrinkage of uterine fibroids. ② It has mild anticoagulation and inhibits thrombosis, prevents blood stasis and scarring, and is beneficial to the treatment of uterine fibroids. ③ It has a certain effect in promoting the assimilation function in the body, which can enhance physical fitness and improve disease resistance. ④Acute toxicity test shows that the toxicity of this prescription is very low. Uterine fibroids belong to the category of lumps in Chinese medicine, and their formation is nothing more than the accumulation of righteousness, deficiency and evil, and the mixture of deficiency and excess. Professor Luo Yuankai focused on the cause of this disease and adapted this prescription based on the Juhe Pills in "Jisheng Prescription" and the Lihe Powder in "Jingyue Quanshu". In the prescription, lychee cores, orange cores, chestnut shells, fennel, toodandan seeds, and agate root are used to regulate qi and disperse stagnation, relieve pain and eliminate phlegm; Curcuma zedoary promotes qi and breaks blood, and removes stagnation; seaweed and raw oysters soften and dissipate stagnation; Codonopsis pilosula replenishes qi. Strengthen the spleen; Sichuan Duan nourishes the kidneys and strengthens muscles; Polygonum multiflorum and Gangmin roots nourish blood and stop bleeding; Motherwort activates blood circulation and regulates menstruation, promotes blood circulation and disperses blood stasis, and can significantly enhance the contraction of uterine muscles. Taken together, the comprehensive formula can attack and defend, integrates nourishment in attack, and dissipates in dispersion. It can promote qi and dissipate stagnation, soften hardness and restrain astringency, replenish qi and activate blood circulation, so it has a good effect on uterine fibroids.

The source of the prescription is Luo Qinghua, et al. Clinical experience in treating 150 cases of uterine fibroids with Juli Sanjie Pills. New Chinese Medicine, 1990, (8): 27.