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Why does my whole body hurt after taking febuxostat tablets for gout?
Why does gout hurt all over after taking febuxostat tablets? The reason for eating febuxostat pain is usually two cases, one is in the acute arthritis attack has not been completely relieved, febuxostat belongs to the inhibition of uric acid production of drugs, is a kind of uric acid lowering drugs, if the addition of febuxostat in such a period of time, it will lead to sudden fluctuations in the level of blood uric acid, which will aggravate the arthritis symptoms, or to induce a re-attack. Another situation is that in the chronic arthritis period, if the amount of febuxostat application is too large, can also cause arthritis attack and pain.

After taking Febuxostat tablets for a gouty attack, the body aches in all directions, which is the "pain of dissolving crystals" produced by Febuxostat. After taking febuxostat, the blood uric acid level decreases steeply, and the joint cavity, the blood uric acid in the tissue fluid (decreases faster than the blood uric acid) to produce a gradient direction difference. As a result, the blood uric acid in the joint cavity and tissue fluid migrates to lower concentrations in the circulatory system, causing the uric acid crystals adhering to the bursae and cartilage tissues of the bones and joints to dissolve into smaller uric acid crystals. In contrast to these higher volume, smooth structure of the urate crystals, this new, fine uric acid crystals are more likely to be phagocytosis of the body's immune cells, resulting in a gouty attack of subacute onset, that is, what we say, "the pain of the crystals".

"The pain of dissolving crystals" often arises in the early stages of uric acid treatment, as if the phoenix nirvana can have to go through some burning general, serum uric acid level down to all normal also have to go through a lot of hard work. Therefore, once in taking uric acid medicine period feel the pain, do not panic, this is also the blood cells in the blood uric acid level gradually reduce the main performance.

So once you feel the pain while taking uric acid medicine, don't panic, this is the blood level of uric acid in the blood gradually reduce the performance. However, for patients who are very "pain intolerant", doctors will appropriately reduce the dose of "febuxostat", and at the same time take a low dose of non-steroidal anti-inflammatory drugs or colchicine. The pain of gout is manifested as red, swollen and hot pain in the joints, which is closely related to heat, and many symptoms can be relieved by adjusting the medication according to the body type from the perspective of clearing heat.