In winter, many people buy grapefruits to eat. So, can you take medicine after eating grapefruit?
Can grapefruit and medicine be taken together
Medicine + grapefruit = taking poison? This is true! Furanocoumarins, naringenin, bergamot, etc. contained in grapefruit The active ingredient can inhibit the activity of a metabolic enzyme in the human body, thereby affecting drug metabolism and excretion from the body. This may cause a large amount of drug to accumulate in the body, causing the drug to be overly effective, aggravating adverse reactions, and even causing poisoning. So, which drugs are the "dead rivals" of grapefruit?
Drugs that cannot be taken with grapefruit
1. Do not take grapefruit with lipid-lowering drugs: if you are taking Atovava Patients who take grapefruit while taking lipid-lowering drugs such as statins, lovastatin, and simvastatin are more likely to develop muscle pain, rhabdomyolysis, and in severe cases, acute renal failure. Clinical observation has found that when patients with hyperlipidemia take one lovastatin (also known as lipid-lowering) with a cup of grapefruit juice, the result is equivalent to taking 12 to 15 lovastatin pills with a glass of water. The patient will therefore Muscle pain and even kidney disease may occur.
2. Do not take grapefruit with antihypertensive drugs: Since grapefruit itself also has antihypertensive effects, and it can also increase the concentration of antihypertensive drugs in blood samples, taking nifedipine, nimodipine, and vitamin C at the same time is not recommended. Eating grapefruit or drinking grapefruit juice while taking antihypertensive drugs such as Lapamil is like overdosing on the drug, which can cause a sudden drop in blood pressure, which may cause dizziness, palpitation, and fatigue in mild cases, or induce angina, myocardial infarction, or stroke in severe cases.
3. Do not take grapefruit with sedatives and sleeping pills: grapefruit will increase the possibility of diazepam, midazolam and other drugs causing dizziness and drowsiness, especially for high-altitude workers and drivers. Notice.
4. Do not take grapefruit with birth control pills: grapefruit will hinder women’s absorption of birth control pills. Women taking birth control pills may experience contraceptive failure if they eat grapefruit after sex. A study in the United States showed that grapefruit has the most prominent impact on birth control pills. Experts say, "If a woman who takes birth control pills eats 1 to 2 grapefruits after sex, or takes birth control pills directly with a large glass of grapefruit juice, then she may become a mother. The reason is that grapefruit hinders the development of a mother." It affects women’s absorption of contraceptive pills.”
5. Do not take grapefruit with anti-allergic drugs: grapefruit may induce adverse reactions to terfenadine and other anti-allergic drugs, causing dizziness, palpitations, and arrhythmia. and other symptoms.
6. Do not take grapefruit with immunosuppressants: grapefruit can increase the blood concentration of immunosuppressants such as cyclosporine and increase liver and kidney toxicity. If this kind of medicine is taken together with fruits such as grapefruit for a long time, there is a risk of inducing tumors.
Who cannot eat grapefruit?
1. Patients with high blood pressure should not eat grapefruit, especially grapefruit. Because it can interact with the drugs that patients with hypertension take daily, increase the blood concentration of the drug, significantly reduce blood pressure, and pose a threat to physical health.
2. Grapefruit is cold in nature, so people with weak body should not eat more.
3. Women taking birth control pills should not eat grapefruit
A study in the United States showed that grapefruit has the most prominent impact on birth control pills. Experts say, "If a woman who takes birth control pills eats 1 to 2 grapefruits after sex, or takes birth control pills directly with a large glass of grapefruit juice, then she may become a mother. The reason is that grapefruit hinders the development of a mother." It affects women’s absorption of contraceptive pills.”
4. People with poor liver function should not eat grapefruit
Pomelo contains an unknown active substance that affects the human intestine. An enzyme has an inhibitory effect, which interferes with the normal metabolism of the drug and significantly increases the blood concentration. It affects liver detoxification, damages liver function, and may also cause other adverse reactions and even poisoning.
What foods should not be eaten with grapefruit?
Type 1: Crab
Pomelo cannot be eaten with crabs. Eating them together will irritate the gastrointestinal tract and cause abdominal pain, Symptoms such as nausea and vomiting.
The second type: cucumbers and carrots
Eating them together will destroy the nutritional value of vitamin C in grapefruit.
The third type: Pork liver
Pork liver is rich in copper, iron, zinc and other components. Once it meets the vitamin C in grapefruit, it will accelerate the oxidation of metal ions and cause Destroy the original nutritional value.