The main symptom of fly maggot disease is mechanical irritation of the host or patient by the fly maggots. The hairs, hooks, spines, and migrations on the body surface of the maggots irritate the body wall of the host. The patient may feel stinging, pain, itchiness, foreign body sensation, migratory sensation, etc. in certain parts of the body. For example, patients with nasal maggots may sneeze and feel a foreign body sensation in the nose. Genitourinary fly maggots may feel tingling, migrating, frequent, urgent and painful urination in the lower abdomen, urethra and vagina. Dermatophagoides patients will feel subcutaneous cone pain, subcutaneous migratory sensation, and even subcutaneous tunnels can be seen after the fly maggots migrate. In addition, fly maggots carry bacteria on their body surface, which may cause infection. In nasal maggots, the maggots may enter the cranial cavity through the sinuses, causing serious consequences and even death. Fly maggots that cause ocular fly maggots may enter the interior of the eye, destroying the tissues inside the eye and causing blindness. Some fly maggots feed on host body tissues, such as those of Trypanosoma spiralis. The consequences can be severe, even death.