Diabetes is a chronic disease, and having diabetes means a lifetime of watching your blood sugar, controlling your diet, and exercising. So what are the signs in the body that diabetes is worsening?

First: blood sugar control. If you originally took glucose-lowering drugs and took 10 units of insulin, your blood sugar could always be well controlled. But recently you've realized that the medication isn't working, and your blood sugar is still high even with insulin, which means you may need to increase the amount of insulin, or increase the dosage and adjust your medication.

Second: weight loss all the time. My mother's diabetes was discovered when she kept losing weight inexplicably, and at first it was always thought to be due to exertion. If you were in stable weight control and all of a sudden you have rapid weight loss again, it's important to consider if your diabetes is getting worse.

Third: itching all over, arm pain, leg pain everywhere. When diabetic patients with peripheral neuropathy, there will be itching all over the body, unexplained arm pain and other abnormalities. If you pay close attention to hygiene shower all day, and there is no labor but is itchy and painful, it is likely to have developed peripheral nerve damage.

Fourth: eyes can not see clearly. One of the complications that diabetics are prone to is the lesion of the fundus of the eye. If it is not able to be treated in time, it is likely to lead to blindness. If your eyes suddenly become blurred, you must pay attention to whether the diabetes has worsened, it is best to go to do a fundus examination.

Diabetes is a chronic disease, early, high blood sugar does not cause particular damage to the body, patients often do not feel the existence of the disease, or only "three more and one less" and other minor manifestations, with the passage of time, the body in the role of high blood glucose, and gradually there will be a variety of complications, both acute and chronic. Complications, both imply the deterioration of diabetes

Acute complications:

I. Diabetic ketoacidosis (DKA) refers to the diabetic patients in the role of various triggers (type I can occur spontaneously), such as infection, insulin is obviously insufficient or treatment interruption, surgery, trauma, etc., resulting in hyperglycemia, hyperketonuria, ketonuria, dehydration, electrolyte disorders, metabolic acidosis, and other changes in the blood indicators as the main features of the internal emergency, the main characteristics of the diabetes mellitus. The main characteristics of the internal medicine emergency, early symptoms are polyuria, thirst and weight loss, with the gradual increase in blood glucose or the duration of prolonged, neurological symptoms, including drowsiness, neurological signs of localization and confusion, and in the late stage can develop to coma.

II. Hyperosmolar hyperglycemic state (HHS), also known as hyperosmolar hyperglycemic nonketotic state (HHNK), HHS is usually characterized by the presence of more severe hyperglycemia without ketoacidosis, and the progression of the disease is more insidious, common in the elderly. About 2/3 of the patients have no history of diabetes before the onset of the disease, or only mild symptoms, usually in infections, acute gastroenteritis, pancreatitis, cerebrovascular accidents and other triggers, often confusion and coma, and some patients may also have a mild hemiparesis or hemianopsia, epilepsy.

Chronic complications:

I, diabetic foot, this is my deepest impression of diabetic complications, internship with the teacher cared for a case, the bones and ligaments can be seen, the whole 2 months to recover, the stench is still very clear, but also in the orthopedic department has seen because of diabetic foot amputation of the patient. Diabetic foot refers to the foot pain, sensory loss, deep skin ulcers, gangrene and other lesions caused by a variety of factors such as bacterial infection due to foot vascular and neuropathy. Preventive measures: the feet should be checked daily to see whether there are skin breakage, blisters, swelling or redness between the toes, under the toes and at the place of pressure; wear loose soft-soled shoes; wash the feet with warm boiled water every night (test the water temperature before washing the feet), and cut the fingernails which should not be too short.

Two, atherosclerosis High glucose content in the body will lead to vascular endothelial function inhibition, as well as insulin, growth hormone, catecholamines and other hormone content is too high, will directly or indirectly lead to the formation of atherosclerosis. Mainly violates the aorta, carotid artery, coronary artery, cerebral artery, renal artery and the arteries of the limbs, and we usually recognize atherosclerosis, blood vessel blockage or rupture will cause the corresponding diseases, such as coronary heart disease, stroke, cerebral hemorrhage, etc., peripheral arterial atherosclerosis of the limbs is usually dominated by the lower limb arterial lesions, manifested as lower limb pain, sensory abnormality and intermittent claudication.

Three, microangiopathy microvascular can also be understood as capillaries, here is the main place of material exchange, in which the retina, kidneys, nerves, muscles, myocardial tissues are most susceptible to the erosion of hyperglycemia, and diabetic nephropathy and retinopathy are the most important.

Diabetic nephropathy: Diabetic nephropathy is one of the most serious microvascular complications of diabetes, and is one of the main causes of death in diabetic patients. The development of diabetic nephropathy can be divided into 5 stages: the early stage of diabetes mellitus; glomerular capillary basement membrane thickening stage; early nephropathy; clinical nephropathy stage; uremia stage; diabetic retinopathy: retinopathy is the main feature of diabetic microangiopathy, and also lead to diabetic patients with the main cause of blindness, according to its fundus changes can be divided into 6 stages. Cataracts, glaucoma and iridocyclopathy can also occur in diabetic patients. Diabetic cardiomyopathy: diabetic patients with microangiopathy in the heart, the myocardium will appear extensive focal necrosis leading to diabetic cardiomyopathy, often induced arrhythmia, heart failure and even lead to cardiac arrest.

four, neuropathy, peripheral and autonomic nervous system involvement is the most common diabetic complications, and the duration and severity of hyperglycemia is an important risk factor for diabetic neuropathy in patients with type 1 or type 2 diabetes. Sorbitol accumulation, disruption of the hexosamine pathway, disruption of the protein kinase C pathway, and increased oxidative stress are all mechanisms associated with diabetes leading to neuropathy. The lesion site to the peripheral nerves is the most common, generally symmetrical, lower limbs than the upper limbs, slow progress, the performance is often abnormal sensation of the limbs, the distribution of socks or gloves, accompanied by numbness, pins and needles, burning, or such as stepping on the cotton cushion; when the autonomic nerves innervating the gastrointestinal pathology appeared in the delayed gastric emptying, gastric paralysis, gastric paralysis, the performance of gastric distension, belching, indigestion, and so on.

Fifth, diabetic heart disease, that is, diabetic patients with heart disease, mainly coronary artery disease, diabetic cardiomyopathy and autonomic nerve damage to the cardiac arrhythmia, etc., the survey shows that diabetic heart disease caused by the death of diabetic patients accounted for 60% -80% of the total number of deaths.

Sixth, a variety of infections Due to long-term high blood sugar will inhibit the body's immune function, so diabetic patients often occur folliculitis, boils, carbuncles and other suppurative skin infections, but also long pharyngitis, chemosis and other upper respiratory tract infections, as well as pyelonephritis, cystitis and urethritis and other urinary tract infections.

See the harm of diabetes on the human body is very big, any one of these complications can give diabetic patients with great physical and psychological pain, consume a lot of financial and material resources. We must control our blood glucose well under the pull of the five carriages of diet, exercise, medication, blood glucose monitoring and diabetes education to avoid the complications mentioned above and to live happily with our families!