Specialty drugs for the treatment of colitis
1, antibiotics: light poisoning patients can not use antibiotics. Acute fulminant and toxic colonic dilatation, the application of broad-spectrum antibiotics, should do bacterial culture before use. Penicillins, chloramphenicol, colindamycin, tobramycin, new types of cephalosporins and vanguardin can be used as appropriate. To avoid gastrointestinal symptoms, antibiotics should not be taken orally.
2, mirex: these drugs can inhibit inflammation and immune response, alleviate the symptoms of toxicity, especially in view of some of the common co-existing diseases and arthritis, uveitis and erythema nodosum, hormone therapy has been more effective in the near future, the efficiency rate of up to 90%. In addition, the hormone can also increase the patient's appetite, improve the patient's mood. Prednisone 15mg/day, small dose maintenance can significantly reduce the recurrence rate. The shorter the duration of the disease, the better the efficacy, more than one year duration of the effective rate of sixty to seventy percent.
3, sulfonamides: this drug is mostly used in light and medium-sized patients. The starting dose is 0.5g, 4 times a day orally. Every 2 to 3 days to increase the severity of the disease and the use of corticosteroids to achieve remission of the case, you can also use sulfonamides as a maintenance therapy; but the sudden onset of severe disease, not applicable to the treatment of this product. Other antibacterial drugs are not suitable for the treatment of ulcerative colitis, except when there is toxic megacolon and septic complications.
4, microecological class: microbiological drugs are the first of contemporary colitis patients, especially Zangling Sucralose. Because they are biological products have no side effects. It is a special nutrient source of beneficial bacteria, which can proliferate bifidobacteria at a rate of 40-103 times, regulating the balance of gastrointestinal flora. It is effective in gastritis, gastric ulcer, colitis, constipation, bad breath and diarrhea.
Principles of medication for the treatment of colitis
(1) Diet: Get enough rest, avoid fatigue and mental overstress. Give less irritating easily digestible nutritious diet, try to avoid rough fiber-containing foods, temporarily do not eat milk and dairy products. Supplement fluids and electrolytes, vitamin B and calcium. Take iron preparations and folic acid to treat anemia. Serious illness, frequent diarrhea, severe malnutrition of patients, can give a period of gastrointestinal elements of the diet or extra-gastrointestinal nutrition.
(2) anti-infective drugs: salicylazo-sulfapyridine on the treatment of ministries of colitis, to prevent complications have better efficacy. Some cause nausea, vomiting, headache, rash, granulocytopenia, anemia and liver dysfunction. If it is not effective and there are adverse reactions, it can be changed to metronidazole. Neomycin and phthalothiazole are also effective.
(3) hormone therapy: adrenocorticotropic hormone, hydrocortisone and prednisone can improve the systemic condition, so that the course of the disease is alleviated, the number of fecal discharge is reduced, the recurrence of symptoms is reduced and the appetite is increased. However, they are not effective in some patients and can perforate ulcers, which bleed and heal slowly. It is now believed that the scope of application is relatively small, for acute flare-ups or early onset of severe patients can make the symptoms significantly reduced, the condition improves; for long-term recurrent episodes of the effect is not satisfactory; pro-corticosteroid units dissolved in glucose solution, intravenous drip, after the improvement of the symptoms switched to intramuscular injection. Hydrocortisone is given intravenously, with gradual tapering after symptom relief. Corticosteroids are more effective than cortisone in relieving symptoms, but less effective than cortisone in maintaining relief. This treatment should not be continued for more than 2 weeks without improvement in symptoms.
(4) immunosuppressive drugs: azathioprine, once a day, can change the course of the disease, inhibit the clinical manifestations, but can not change the underlying disease, often used in the quiescent period to reduce relapse, but also may be poisoned, it should be noted. 6 thiopurine (6-MP) and the hormone combination can reduce the symptoms.
Dietary principles of colitis
1, less fiber, low-fat food has the role of promoting intestinal peristalsis, stimulating the intestinal wall, but it is not easy to digest, is not good for the intestinal tract, so it should be limited.
2, pay attention to supplemental protein and vitamins.
3, chronic enteritis, such as dehydration and low sodium phenomenon, should be timely supplementation of light saline, consumption of vegetable leaf soup to supplement the loss of water, salt and vitamins.
4, exhaust, diarrhea is too strong, should eat less sugar and easy to produce fermentation of food: such as potatoes, beans, milk and so on.
5, persimmons, pomegranates, apples contain ellagic acid and pectin components, are astringent antidiarrheal effect, chronic colitis can be consumed in moderation.
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