Heat-clearing and detoxifying medicines are a class of medicines that mainly detoxify heat, fire and epidemic poisons, including honeysuckle, forsythia, dandelion, chrysanthemum, radix et rhizoma, Andrographis paniculata, Fishweed, bear's bile, mung bean, etc. They can be used to treat sore throats, boils on the nose and throat, mumps, dysentery of heat, carbuncle and furuncle, salmonella, insect and snake bites and scalded by fire, etc. Modern research analyzes that these medicines have varying degrees of antimicrobial activity and are resistant to a variety of bacteria, and some of them are also resistant to drugs. Modern research analysis, purgative and detoxifying drugs have different degrees of antipathogenic microbial effect, and can resist a variety of bacteria, not easy to produce drug resistance, part of the drug also has anti-inflammatory, antipyretic, antiviral and other effects. In the clinical application of such drugs, if the patient's fire and heat blazing, should be used with heat-clearing and fire-eliminating drugs; if there is also dampness, should be used with diuresis, dampness, or dampness drugs; if there is also a deficiency of qi and blood, should be matched with drugs to replenish the qi and nourish the blood, and so on. It should also be noted that most of the heat removing drugs are cold, easy to hurt the spleen and stomach, so do not serve more long service, the disease is over.