At present, it is suggested that acute gout attack should be treated as soon as possible (generally within 24 hours), among which non-steroidal anti-inflammatory painkillers should be the first choice, such as etoricoxib, diclofenac sodium, celecoxib and loxoprofen sodium. However, we should pay attention to the adverse reactions of drugs to cardiovascular and gastrointestinal tract. Colchicine is also commonly used for acute gout attacks. However, due to the high incidence of gastrointestinal adverse reactions, it is easy for patients to stop taking the drug because of intolerance. Therefore, colchicine can be considered for patients with acute gout who have contraindications to the use of non-steroidal anti-inflammatory painkillers. If the patient's condition is serious, the conventional drug treatment effect is not good, or there are contraindications to the use of non-steroidal anti-inflammatory painkillers and colchicine, short-term use of glucocorticoid can be considered to control clinical symptoms. In addition, patients with acute gout should drink plenty of water to promote uric acid excretion, and at the same time, drinking alcohol and eating food such as animal offal and seafood are prohibited. At present, drugs are still a quick and effective way to relieve joint symptoms in acute gout attacks, but because they are used under the guidance of doctors, patients should actively control the level of serum uric acid, reduce the number of acute gout attacks and control the condition as a whole.