On January 14, 2021, according to the announcement issued by the State Food and Drug Administration, the State Food and Drug Administration canceled the drug registration certificates of phenolphthalein tablets and phenolphthalein lozenges. After the marketing evaluation of phenolphthalein tablets and phenolphthalein lozenges, it was decided to stop the production of phenolphthalein tablets and phenolphthalein lozenges in my country because it has serious adverse reactions. After use, its effect on patients may do more harm than good, causing serious adverse effects. reaction, so what are phenolphthalein tablets? What adverse reactions will there be? Let’s take a look. A detailed introduction to phenolphthalein tablets

Phenolphthalein tablets and phenolphthalein lozenges are what we often call "fruit guide tablets". Their main component is phenolphthalein, and its chemical name is: 3,3-bis(4-hydroxybenzene) base)-1(3H)-isobenzofuranone, its molecular formula is C20H14O4, and its molecular weight is 318.33. Phenolphthaleins are often used clinically to treat habitual and stubborn constipation. They are also often used as intestinal cleaning agents during colon and rectal endoscopy or enema examinations to reduce feces and other objects in the intestines to reduce obstruction of the field of view in the microscope. Its mechanism of action mainly acts on the colon and is a contact laxative. Phenolphthalein is decomposed under the action of alkaline intestinal fluid to form soluble sodium salts, which then stimulate the nerve plexus of the intestinal wall, usually stimulating the nerves in the intestinal wall and acting on the intestines. smooth muscle, thereby increasing intestinal peristalsis, and at the same time inhibiting the absorption of water in the intestine, causing water and electrolytes to accumulate in the colon, thereby producing a cathartic effect. Adverse reactions of phenolphthalein tablets

The main adverse reactions of phenolphthalein tablets and phenolphthalein lozenges are that long-term use will inhibit the disorder of water, electrolytes and vitamins in the intestine and inhibit their absorption, because our human body needs There are strict controls on electrolytes such as sodium, potassium ions, and calcium ions, so don’t underestimate the small amounts of electrolytes in our bodies. They will affect the homeostasis of the body’s internal environment. For example, our common electrolyte disorders can be seriously life-threatening. Disease------hypokalemia can induce arrhythmia or syncope. It can also cause loss of nutrients in our body and cause anemia and other problems. Short-term medication will not cause too many problems, but long-term dependence Sexual use of such drugs will produce the above adverse reactions, and some patients will also have more serious adverse reactions, such as enteritis, bleeding, etc. By discontinuing this type of drug this time, we may have discovered more serious adverse reactions. Why have phenolphthalein tablets and phenolphthalein lozenges been discontinued?

We ordinary people may not know much about this, but in many countries, phenolphthalein drugs have long been withdrawn from the market due to their adverse reactions. Secondly, in our daily life, we often see serious drug abuse. The most common one is the abuse of antibiotics. There are also serious drug abuses of phenolphthalein drugs. Phenolphthalein tablets are prescription drugs. It is not allowed to be purchased or taken without the permission of a doctor. Generally, doctors will not prescribe medicine for more than three days, and they are required to stop taking the medicine immediately after defecation. However, many unscrupulous merchants use its cathartic effect to make weight loss pills and health products. The Food and Drug Administration of our country has long banned the addition of phenolphthalein into health products. Many people who lose weight have purchased weight loss pills and health products containing phenolphthalein, and have been taking phenolphthalein drugs for a long time without realizing it. At the same time, the author hopes that everyone can lose weight reasonably and do not use diet pills. Obesity not caused by hormones is mostly caused by irregular life. Losing weight through reasonable exercise and healthy diet is the most effective way to lose weight. I also wish you all the best. A healthy and healthy body.