Neurasthenia when, mainly for the patient's clinical manifestations to give symptomatic treatment, basic drugs such as glutamine, vitamin B1, vitamin B12 (methylcobalamin), and nerve resurrection agents such as olanzapine, fennecarisetine, or brain capsule, such as the basic drugs. Patients with neurasthenia are usually combined with sleep disorders, and in the short term, they should apply drugs to improve sleep, including benzodiazepines such as alprazolam, eszopiclone, and new non-benzodiazepines such as zolpidem, dexzopiclone, zopiclone, etc., and they can also apply proprietary medicines such as Anshen Tonic Brain Liquid, Anshen Capsules, and Shumian Capsules, etc., to improve their sleep.

In addition, neurasthenia patients are mostly combined with mild depression or anxiety, can be appropriate application of antidepressant and anxiety drugs, commonly used 5-hydroxytryptamine receptor antagonist such as citalopram, or 5-hydroxytryptamine and norepinephrine reuptake inhibitors such as duloxetine, norepinephrine, as well as specific 5-hydroxytryptamine receptor antagonist such as mirtazapine. The use of antidepressants, anxiety drugs and drugs to improve sleep, coupled with a combination of glutamine and other regulation, can improve the clinical symptoms of neurasthenia.