Semen Strychni, also known as Radix Aconiti Kusnezoffii, Semen Momordicae, Plantago asiatica and Dabafang, is a mature seed of Semen Strychni of the family Strychnaceae. It tastes bitter, cold and highly toxic. Entering the liver and spleen meridians. Efficacy: detoxifying and resolving hard mass, activating collaterals and relieving pain. It can be used for treating rheumatism, numbness, paralysis, carbuncle, swelling and pain, and traumatic injury. "The function of dredging meridians and joints is far better than other drugs" (Experience of Western Medicine). The long-term clinical application of nux vomica shows that the curative effect is exact, but this product is highly toxic and must be strictly processed before it can be used as medicine. The processing quality and toxicity of Semen Strychni are analyzed as follows. The purpose and significance of processing 1 nux vomica is mainly composed of alkaloids, accounting for about 2% ~ 5%. At present, 16 alkaloids have been isolated, among which brucine (brucine) and brucine (brucine) are the most important, each accounting for 1% ~ 65438. The best effective dose is close to the mild toxic dose, that is, the safe range of treatment is small, and a little careless dose will cause toxic reaction, so doctors have always attached great importance to its treatment. The purpose of its processing is to reduce toxicity, ensure curative effect, remove fur, make hard medicinal materials brittle and easy to crush, which is beneficial to the absorption of effective components. According to the related experimental research, the processing has certain influence on the contents of strychnine and brucine in Semen Strychni. High temperature treatment can significantly reduce the content of strychnine, especially the content of brucine, and most of the brucine with high toxicity and poor curative effect can be removed. Different auxiliary materials such as vinegar roasting, frying and licorice processing can reduce toxicity, and the contents of strychnine and brucine in vinegar soaked products can be greatly reduced. After cooking with skim yogurt, brucine can be removed by 60%, but it has little effect on strychnine, which fully shows that its toxicity can be reduced without losing effective components through processing.