1, clinical manifestations of individual differences, some patients may be asymptomatic.

2, the characteristics of clinical manifestations

(1) chronic process, repeated attacks.

(2)Periodic and seasonal episodes (in autumn, winter or winter and spring)

(3)Rhythmic epigastric pain

Gastric ulcer pain after eating, duodenal pain on an empty stomach before meals, relieved by eating, mostly accompanied by nocturnal pain.

Treatment

The purpose of treatment is to eliminate the cause of the disease, relieve the symptoms and promote the healing of ulcers, reduce the recurrence of ulcers and avoid complications.

1, general treatment

Emphasis on the regularity of life, to protect the healthy mental and psychological state, quit smoking and alcohol, avoid NSAID and other drugs.

2, drug therapy

(1) to reduce the acidity of the stomach drugs 1) antacids: to relieve ulcer pain and a better effect, less alone in the treatment of peptic ulcer, can be used as an adjunctive treatment to enhance pain relief. 2) acid suppression drugs H2 receptor antagonists

a cimetidine 0.4 twice a day

b Ranitidine 0.15 twice a day. Oral

Proton pump inhibitors:a

Omeprazole 20mg, once daily orally;

b

Lansoprazole

30mg, once daily orally

The course of treatment is 8 weeks

(2)Mucosal protective agents

1)Aluminum thioglycollate 1.0g three times daily after meals

2)Potassium citrate 240mg twice daily orally.

3)Prostaglandin (misoprostol) 200ug, 4 times daily orally.

(3)Eradication of HP infection

Triple therapy with proton pump inhibitors

Triple therapy with proton pump inhibitors and two of the three antibiotics, clarithromycin, amoxicillin or metronidazole (tinidazole).

(4)Prokinetic drugs

1)Cisapride 5-10mg, three times a day, orally before meals.

2)Domperidone 10mg, three times a day, orally before meals.

3. Indications for surgical treatment: with acute gastric perforation, pyloric obstruction, massive bleeding and malignant ulcers and other comorbidities.