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Which one is better for treating high blood pressure, An Neizhen or Shi Huida?

Anaizhen and Shihuida are two antihypertensive drugs with significant efficacy. The main component of Aneizhen is amlodipine besylate, and the main component of Shihuida is levamlodipine besylate. Both Aneizhen and Shihuida are dihydropyridine calcium antagonists. The contraction of cardiac muscle and smooth muscle depends on extracellular Calcium ions enter cells through specific ion channels. It can selectively inhibit the transmembrane entry of calcium ions into smooth muscle cells and cardiomyocytes, and has a greater effect on smooth muscle than on cardiac muscle. Anneizhen and Shihuida are both peripheral arterial dilators, which directly act on vascular smooth muscle to reduce peripheral vascular resistance, thereby lowering blood pressure. Patients with mild to moderate hypertension can reduce supine and standing blood pressure 24 hours a day if taken once a day. Long-term use does not cause significant changes in heart rate or plasma catecholamines. Its antihypertensive effect is stable, the antihypertensive effect is dose-related, and the antihypertensive amplitude is related to the blood pressure before treatment. The precise mechanism by which An Neizhen and Shi Huida relieve angina is unclear. Both Anezhen and Shihuida can be used to treat hypertension and angina pectoris, especially spontaneous angina pectoris. After oral administration, the absorption is complete but slow, the antihypertensive effect is stable, the difference between peak and valley values ??is not big, and the therapeutic effect is good. It is safe to use in patients with obstructive pulmonary disease, well-compensated heart failure, peripheral vascular disease, diabetes, and lipid abnormalities. Anneizhen and Shihuida have similar efficacy and effects. They are both drugs for treating high blood pressure and angina pectoris. Shi Huida is a chiral split optically pure drug. The efficacy of levamlodipine is 1,000 times that of dexamlodipine. The efficacy is better than Amlodipine, but the price is relatively higher. An Neizhen and Shi Huida each have their own strengths, and patients can choose according to their actual conditions. KangAiduo introduces medicines in a scientific and objective manner, serves you with professional medical knowledge, correctly executes doctors' prescriptions, and puts forward reasonable suggestions from pharmacists. It is a legal online pharmacy. KangAiduo provides you with low-priced, absolutely authentic and high-quality medicines.