1, antibacterial effect

Poria cocos decoction 100% plate drilling method has inhibitory effect on Staphylococcus aureus, Escherichia coli and Proteus. Poria cocos has no bacteriostatic effect on test tube method. The ethanol extract of Poria cocos can kill leptospira in vitro, but the decoction is ineffective.

2, the influence on the digestive system

Poria cocos has a direct relaxing effect on isolated intestine of rabbits, a preventive effect on ulcer caused by pyloric ligation in rats, and can reduce gastric acid. In addition, it has obvious protective effect on liver injury induced by carbon tetrachloride in rats, significantly reducing the activity of alanine aminotransferase and preventing hepatocyte necrosis.

3. Influence on blood system

The aqueous extract of Poria cocos containing water-soluble small molecular polysaccharides can increase the level of 2,3-DPG in isolated healthy human erythrocytes by about 25%, and can effectively delay the depletion of 2,3-DPG during incubation.

4. Influence on central nervous system

Fuling decoction was injected intraperitoneally at the rate of 5- 10g/kg, which had sedative effect on mice with or without caffeine in advance. Synergistic effect of poria cocos and pentobarbital sodium. Fuling decoction (10g/kg) failed to significantly prolong the anesthesia time of pentobarbital sodium. When the dose was 40g/kg, the anesthesia time was significantly longer than that of the control group, and the sedation index increased with the increase of dose.