The younger the age of treatment, the better the results, with the best results in the first year, the annual height growth of up to 10-12cm, and there may be a decline in the growth rate later.
Hypothyroidism may occur during treatment, and thyroid function needs to be monitored. If necessary, levothyroxine sodium tablets may be added to maintain thyroid function. During use, serum Igf-1 and IGFBP3 levels need to be monitored to understand the efficacy and safety of growth hormone.
Growth hormone deficiency is a growth disorder caused by partial or complete lack of growth hormone synthesis and secretion by the pituitary gland, or due to abnormalities in the molecular structure of growth hormone. The patient's height is below the third percentile of the growth curve of normal healthy children of the same age and sex, or two standard deviations below the mean, and is proportional to the short stature and normal intellectual development.
Currently the incidence is increasing, if found to be idiopathic dwarfism, you can play growth hormone as early as possible to achieve an optimal lifelong height.