So, does the diabetic foot have to be amputated? Of course not. Amputation is not a solution, drug treatment of primary disease is the main measure, can slow down the development of vascular disease. However, if the medication is not effective, vascular surgery is also effective.
Since diabetic foot is caused by insufficient blood supply to the feet, can't the problem be solved by artificially bringing blood to the feet? Yes. This is a traditional procedure that surgeons have been performing for many years. The bridge must be built over the diseased narrow blood vessel, from the base of the thigh to the ankle, otherwise the blood supply to the distal part of the foot will be compromised, and generally speaking, the farther the bridge is built, the better the protection of the distal limb will be. Building a bridge is all about construction. Where do you get the materials? The easiest thing to think of is artificial blood vessels. After many years of application, it is found that artificial blood vessels work well for short distances, but if they are too long, there is a higher chance of internal thrombosis leading to obstruction; artificial blood vessels are also often deflated and cause obstruction where they cross the knee joint. The other material is the patient's own material. The saphenous vein, which runs the entire length of the lower extremity, is ideal. However, the saphenous vein has some disadvantages, namely, the caliber is relatively small, the blood supply is often not large enough, and many patients have problems with the saphenous vein itself, making it difficult to obtain the length of a leg. Dr. Freedman of Boston University in the United States combined the two materials and used artificial vascular material for the section above the knee, and used the saphenous vein for the section spanning the knee and the section below the knee, which is called sequential bypass, which not only meets the blood supply, but also reduces the chances of obstruction, and has a wide range of adaptability, which has been rapidly promoted in the international arena. In our application, we found that the joints of the two sections of grafts and the distal joints are the key to the surgery, so we made improvements in these two parts. The joints of the two materials were originally *** same connected to the human artery, changed to artificial blood vessels themselves connected to the artery, by the saphenous vein and then connected to the artificial blood vessels, to improve the local blood flow patency has certain benefits; the joints of the distal foot and wrist were enlarged, and the veins accompanying the artery were changed the direction of the blood flow, so that the point of saphenous vein injection from a point to two points, the foot stepped on two boats, creating the formation of a *** same outflow tract technique that drives blood flow.
As the foot regained sufficient blood supply, the dying cells and tissues in the ulcerated area of the toes quickly regained their vitality, and the ulcers could heal quickly. The patient feels much warmer feet and no pain in the calf when walking. For the toes or part of the foot surface have been necrosis, of course, the dead can not come back to life, but due to the abundant blood supply, the edge of the necrotic area no longer continue to spread upward, the demarcation line between the normal and abnormal tissues is becoming more and more obvious, and finally, necrotic toes can be detached by themselves, difficult to detach the necrotic portion of the use of surgical methods of excision will be able to, avoiding the " The high level amputation of the leg is avoided, and the function of the limb is fully preserved, which is very beneficial to the improvement of the patient's quality of life.
China has "bloodletting therapy", which is in the patient's necrotic skin or under the side of the
needle piercing, so that the congested blood release, take away the necrotic tissue, foot ulcers will gradually improve.
A patent to iron out the pain of 10,000 people sores
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By chance, internist Dr. Zhang Ping is determined to study the medical problem of skin sores. After continuous improvement, her set of formulas and therapies became mature, and was awarded a Chinese invention patent. So she changed her profession to become a specialist, has developed into a large-scale specialized hospital, for tens of thousands of patients to relieve the pain. The story tells us that there is a chance and a necessity to produce excellent patents, and that patents need to have a calm mindset from the time they are produced to the time they are implemented and the benefits they achieve are wide-ranging. Before interviewing Jinan Skin Ulcer Hospital, the reporter had gotten a copy of the information about the hospital. Thick folder, in addition to simple text information, the rest are all about the skin ulcer patient parts of the photo, ulcerated wounds, bloody limbs, can only be described as "miserable". It is impossible to imagine how the patient is suffering from this physical and psychological torture. According to the information, due to various reasons caused by the wound does not heal and skin ulceration, is today's medical research in the field of difficult subjects, clinical treatment generally take or skin grafting, or amputation, or declared incurable; a lot of patients are facing amputation or pay the price of the tragedy of life. However, Jinan Skin Ulcer Hospital has created the medical myth of "turning decay into magic", many patients from all over the country will be amputated after the hospital's careful treatment, the vast majority of patients to keep the limbs; up to ten years, decades of wounds do not heal the patients to restore the normal skin. This comes from a Chinese invention patented by Zhang Ping, the president of the hospital - "skin healing cream". Love drove the internist to fill the gap "This is not some ancestral recipe, is my own slowly drilled out." In Jinan Skin Ulcer Hospital in the humble director's office, Zhang Ping talked to the reporter about her patent. Zhang Ping is the "Cultural Revolution" period of growth of the generation, as in that particular era of a worker, peasant and soldier trainees, her theoretical and practical time in the health school added up to only two years. After graduation, she was assigned to Jinan Lixia District Hospital and became an internist. In the early 1980s, an old woman asked Zhang Ping to change her medicine during the Spring Festival, and she agreed. At that time, the old woman had a thumb-sized ulcerated wound on her foot, which required frequent medication changes. When informed that this wound had not healed for eight years, it immediately aroused Zhang Ping's curiosity. As an internist, this kind of chronic skin ulcer was something she had neither learned in class nor seen in relevant materials. In the next few days, she tried to change several medicines for the old lady, but none of them worked. A doctor told her that he would send a plaque to anyone who could cure this wound. Zhang Ping realized that the treatment of this disease is still a medical gap. Zhang Ping likes to challenge in the next few days everywhere to consult the relevant experts, daily access to ancient literature. From Chinese and Western medicine to folk remedies, she studied one by one, and finally to the degree of obsession. Sometimes sleep to the middle of the night, a sudden inspiration, will be hard to sleep husband called up to help. For the ultimate success of this formula, Zhang Ping jokingly called himself a "blind cat caught dead mice", because only six months, the drug to obtain satisfactory results, the foot ulcers of the old lady is also the end of eight years of pain. With the first success, Zhang Ping paid more attention to those skin ulcer patients. Once, she saw a patient in the hospital's surgical department who was wearing a cast because of a fracture and had a large skin ulcer. With a try-and-see attitude, she suggested that this patient use her formula. As a result, the same success was achieved. After that, she continued to improve and refine her formula. In her spare time, she was constantly in and out of the hospital's surgical wards, as well as traveling to patients' homes. She gradually summarized a set of traditional Chinese medicine, external application of traditional Chinese medicine and intravenous drip "trinity" therapy. Later, under the support of the hospital, Zhang Ping did a leave without pay, rented a hospital room, set up a "skin ulcer treatment center. Once, one of her patients said to her, your prescription is so good, you should apply for a patent to protect it. It was 1993, and most people didn't know what a patent was. Zhang Ping from its words, organize their own prescription, to the Shandong Provincial Patent Office to apply for a patent for invention. 1997, her invention patent "muscle healing skin cream" was authorized. The so-called skin sores, is due to diabetes, varicose veins of the lower extremities, vasculitis, bedsores, burns, frostbite, traumatic fracture, osteomyelitis, post-surgical incision does not heal, mosquito bites, anal fissure, anal fistula, hemorrhoids, genital inflammation, and other reasons for the prolonged skin ulceration, the incidence rate is high. As Zhang Ping's popularity continues to increase, the rented hospital outpatient room has been far from enough, with the help of family and friends, she bought a three-story building in Jinan City, Lixia District, in 2003, the creation of the "Jinan Skin Ulcer Hospital". With the increasing number of patients, the three-story building became too small, and she converted the hospital into a six-story building. By now, more than 90 beds are still far from meeting clinical needs, she is actively planning to expand the hospital. "We have a statistic that there are patients from all provinces and cities in the country, except Tibet, who come to seek medical treatment." Zhang Ping said. Since she invented this formula in 1985, tens of thousands of patients have been treated here, and the vast majority of them have recovered. Create a myth special hospital writing legend Zhang Ping's office is full of pictures of skin ulcers, a glance, half of the wall are horrifying pictures. One of the hospital's doctors admitted that people who have never worked as a doctor look at these photos, "it's hard to bear". But these photos in the eyes of Zhang Ping, but has a different meaning, perhaps this represents a responsibility and a kind of care. The patient Dongmou, from Jinan City, Changqing District, the return of the town. 1996 summer, Dongmou feel the pain in the left shoulder, in the local hospital treatment, but the pain worsened, and accompanied by redness and swelling. Soon, the muscle tissue began to turn black and ulcerate. Dong's family rushed him to a provincial hospital in Jinan, where he was diagnosed with "arteriovenous cellulitis". In just a few days, saw the whole left arm muscle ulceration is spreading, and caused serious acute heart failure, acute renal failure, severe anemia and other complications, the hospital issued a critical notice. In desperation, Dong and his family took a chance and came to Jinan Skin Ulcer Hospital. At that time, Dong Mou's entire left arm skin muscle necrosis of more than 80% of the skin, was honeycomb, and extends to the armpit, facial bruises and severe deformation. In the face of this rare disease, all the medical staff present were stunned. Zhang Ping and the hospital experts immediately consultation, developed a rescue program. A week later, the patient's affected limb produced new granules, the honeycomb necrotic tissue gradually disappeared, and the complications began to improve. Half a month later, skin began to grow around the wound. 4 months later, Dong was miraculously cured. Ms. Su from Jiamusi City, Heilongjiang Province, brought her elderly mother to Jinan to seek treatment. Ms. Su to the experts said: mother's left foot in 30 years ago due to burns left a scar, 7 years ago, the scar above a small crack, and gradually expand, and constantly festering. In order to cure her mother, Ms. Su has taken her mother to all over the country to seek medical treatment, however, to bring them is disappointed again and again. Ms. Su, who was eager to treat her mother, searched extensively on the Internet for hospitals that treat this disease, and when she saw the information that Jinan Skin Ulcer Hospital could treat skin ulcers, they came to Jinan with a try mentality. In just nine days, the ulcerated foot surface appeared bright red granulation tissue, the skin gradually healed. The mother and daughter did not dream that 7 years of illness here finally saw the hope. On the wall of the hospital office, hanging a banner presented by an old general of the Jinan Military Region: "wonderful medical skills, the crown of the apricot grove". It turns out that two years ago, the general's partner's left foot due to diabetic gangrene caused by necrosis and ulceration of the toes, diagnosed by the army hospital, must do amputation surgery. After learning the news, the military life of the old general, although the grief to pacify the old partner to accept this cruel reality, but still can not bear to let the old partner in his old age, leaving disability regrets. Introduced by others, please Zhang Ping to the military hospital together with the consultation. After careful diagnosis, Zhang Ping that the old man's feet do not need amputation, even the ulcerated toes can be saved. In order to be prudent, agreed with the military hospital, Zhang Ping to the military hospital for his treatment. Two days later, the inflammation at the patient's wound began to disappear significantly. This made the general overjoyed, and immediately decided to transfer to Jinan Skin Ulcer Hospital for treatment. After more than 40 days of careful treatment, the general's partner fully recovered. Experts from the military hospital rushed to the hospital, and when they saw the effect of the treatment, they said, "Miracle! Miracle!" Zhou, a peasant woman from Qufu. In June last year, due to bicycle accidentally fell on the right foot, in the local health center stitches 6 stitches, after the wound has not healed, has been in the local hospital, the provincial capital of Jinan, a number of hospitals still do not see any improvement. Finally, a provincial hospital diagnosed as suffering from diabetes caused by the wound does not heal, the only clinical treatment is amputation, or will pay the price of life. As a result, more than 60,000 yuan of medical expenses, the right leg below the knee was amputated, the middle-aged peasant girl into a lifelong disability. But the bad luck did not leave, not long after, the surgical sores began to fester, waiting for her will be high amputation. In desperation, Zhou and her husband came to Jinan Skin Ulcer Hospital with the desire to survive, Zhang Ping and colleagues understand the situation and said regretfully, "If you come earlier, you will not let you lose this leg, too bad." The next treatment to make the miracle of reappearance, see the wound healing day by day, Zhou Mou mixed feelings of grief; although the loss of a leg, but life preservation, which makes the original unfortunate Zhou Mou and her husband saw the hope of life. The development of private hospitals difficult to break the financial bottleneck Zhang Ping told reporters that the hospital is in a new stage of development, as with other small and medium-sized enterprises, there is also the financial difficulties. This is because of their high running costs. First, the charges for patients are low; secondly, they are traveling across the country, generating huge travel costs; thirdly, they often reduce or waive fees for patients with family difficulties. It is reported that a hospital has been "sentenced to death" of the transfer of military personnel, wanted to leave the provincial capital of Jinan home "waiting for death", the patient's brother inquired about the hospital. The patient's brother asked about this hospital. When he came to the hospital, his shoulder joint was ulcerated and had been completely empty. After Zhang Ping, president of the examination, diagnosed as "bone tuberculosis". The patient's life was in danger many times during the debridement treatment, and it was Zhang Ping and all the doctors who rescued him from the death line. When he was discharged from the hospital, because the patient's family was poor and owed medical expenses amounted to 50,000 yuan, the hospital proposed to recover only the cost, and the rest of the fee will be waived. But the patient did not agree, insisted that his life is the hospital to save, say what can not owe the hospital money. Eventually, the sum of 50,000 yuan, handed over to the hospital. Zhang Ping said, this is her from the start of the clinic so far received the highest amount of medical fees. But she explained that at that time, because they still need to rent the hospital's operating room, so the cost is relatively high. And now, most of the patients throughout the treatment cost but 3,000 to 4,000 yuan money, more than 10,000 yuan or so. Over the past few years, the hospital for patients to reduce or even subsidize the funds, the accumulation is also a considerable amount of money. From the clinic to the hospital, all the investment is slowly accumulated. Zhang Ping said, during which did not accept any investment. But as a private hospital, it is difficult to have a breakthrough just by relying on your own meager accumulation. "There are still a large number of patients in the community waiting for us to treat, and the existing conditions of the hospital, far from being difficult to meet the needs of patients, the urgent need to be improved, the need to expand, the need to increase equipment, the need to introduce talent, the need to expand the popularity of the hospital, which all need funds." Zhang Ping concluded, "I hope that someone can invest in expanding the size of the hospital, so that more patients are relieved of their illnesses."Reporter testimonials
The Nth mode of patent implementation
In the reporter's contact with the patent holders, the implementation of the patent is generally several ways: one is the transfer, that is, their patents cleanly sold out; the second is the cooperation, and the funding party to sign a cooperation agreement *** with the implementation of the long-term benefits; the third is the implementation of their own, that is, to raise their own funds to develop their own Patented products. Because the nature of the patent product is different, the implementation of various ways in practice also has its own advantages and disadvantages. Zhang Ping's way of implementing the patent seems to be a bit special, the reporter will call it the "Nth mode". The peculiarity is that the implementation of the patent "skin cream" from the minimum investment to start, slowly accumulate, slowly bigger. Although during the period, Zhang Ping also cooperated with a pharmaceutical company, but for various reasons, in the contract period, she did not get the profit commission, only in accordance with the contract to get a few tens of thousands of dollars of cooperation funds, relative to a considerable scale of private hospitals, obviously not enough.The birth of the original invention patent, often cohesion of the inventor of a huge amount of money, time, energy and wisdom invested. But very often, a huge pay does not mean that there is a good market return - this is determined by the market needs as well as the ability to operate the project. Practice has proved that "muscle healing cream" has a broad market prospects, for the moment, the transfer of a "sky-high" is not a luxury. But this "sky-high" is in Zhang Ping personally implemented in the process of gradual social acceptance and recognition. On the other hand, if Zhang Ping does not go through clinical practice, but direct transfer of patents, and is the "lion's mouth" to a million million, I'm afraid the possibility of success is very small. Perhaps the patent is still asleep. At least, tens of thousands of patients through the patent lifted the pain, get a new life, from the contribution to the medical and promote the humane point of view, the merits are immeasurable, can not be measured in money.
Not every patent's social value can be slowly highlighted like this, as the inventor, Zhang Ping's merit is "calm"."Zhuangzi - Miscellaneous - LianYuKou" cloud: Zhu Ping diffuse learning dragon slaying in ZhiliYi, a single thousand gold family. Three years of technology, and no use of their skills. Pay thousands of dollars to learn the art of dragon slaying, only the rich family can afford the cost, but no matter how subtle its technology, really learn to graduate, there will be nothing to do, rather than killing pigs and cows to the reality. According to the ancient rules of master and apprentice, learning to kill pigs, at most, is to follow the master unpaid work, the cost is extremely low. After learning it, one could soon feed his family, and would not be rich, but would not starve either. There is a market only when there is a demand, there is a market only when there is a profit, there is a profit only when there is a success, this is the most "shameless" rule of the market economy. Therefore, Mr. Liu Xuemin, a famous management consultant, believes that the teacher who can charge thousands of dollars to "sell" the concept of killing the dragon Zhili Yi, is the biggest success in the market economy.
A patent project is a "gold bar" or "straw", the final say by the market, always depends on consumers and the public recognition. This requires time to test, the need to overcome the difficulties of bold practice, to achieve "peace of mind", constantly improve the patent technology, more market information, more to grasp the laws of the market. Most importantly, this process is not possible to "make a lot of money", or perhaps to the opposite. Even if the value of the Hershey's jadeite, not after pondering, may not be recognized. This is an important connotation of the Nth model of patent enforcement.