Chronic gastritis refers to various chronic gastric mucosal inflammatory lesions caused by different causes. It is a common disease, and its incidence rate ranks first among various gastric diseases. Since the widespread use of fiber endoscopy, the understanding of this disease has improved significantly. Chronic superficial gastritis, chronic erosive gastritis and chronic atrophic gastritis are common. The latter mucosal intestinal metaplasia often involves the cardia and is accompanied by loss of G cells and reduced gastrin secretion. It can also involve the gastric body, accompanied by loss of oxyntic glands, resulting in a reduction of gastric acid, pepsin and endogenous factors. .

Cause

1. Helicobacter pylori infection, virus or its toxin

It is more common after acute gastritis. The gastric mucosal lesions do not heal for a long time and develop into chronic superficial gastritis. Superficial gastritis. Mainly refers to Helicobacter pylori infection.

2. Irritating substances

Long-term drinking of strong alcohol, strong tea, strong coffee and other irritating substances can destroy the protective barrier of the gastric mucosa and cause gastritis.

3. Drugs

Some drugs such as phenylbutazone, indomethacin, cinchofen, salicylates, digitalis, etc. can cause chronic gastric mucosal damage.

4. Chronic infection of the oral cavity and pharynx.

5. Bile reflux

The bile salts contained in bile can destroy the gastric mucosal barrier, causing hydrogen ions in the gastric juice to back-diffuse into the gastric mucosa and cause inflammation.

6.

7. Environmental changes

Such as environmental changes and climate changes, if people cannot adapt in a short period of time, it can cause disorders of the nerves that control the stomach, gastric juice secretion and gastric function. Uncoordinated movements can lead to gastritis.

8. Long-term mental stress and irregular life.

9. The impact of other diseases

Such as uremia, ulcerative colitis, etc. can cause chronic gastritis.