Other eucalyptus oil also has the functions of expelling wind, relieving pain, relieving itching and relieving summer heat.
1. 1 antibacterial eucalyptus oil has strong broad-spectrum antibacterial effect, and has good antibacterial effect on Staphylococcus aureus, Streptococcus, Mycobacterium tuberculosis, Escherichia coli, Paracolibacillus and various dysentery bacilli.
1.2 Anti-inflammatory eucalyptus oil can obviously inhibit the expression and activation of nuclear factor, tumor necrosis factor and other inflammatory factors [2]. Nuclear factor is an important gene transcription factor discovered in recent years, which is involved in the regulation of many inflammatory factors. Zhou Jianya and others [3] of Zhejiang University Medical College, National Medical Products Administration, Zhejiang Respiratory Medicine Laboratory found that the level of nuclear NF-κB in the lung tissue of rats with chronic bronchitis induced by SO2 increased, thus increasing the transcription and expression levels of inflammatory mediators, cytokines, chemokines and proteolytic enzymes. After treatment with eucalyptus globulus oil, the level of NF-κB decreased obviously, indicating that eucalyptus globulus oil can prevent NF-κB from entering the nucleus and inhibit its activity, thus exerting its anti-inflammatory effect. Another study showed that eucalyptus globulus oil pretreatment could prevent the nuclear translocation of NF-κBp65 induced by LPS, thus inhibiting its active function [4]. Juergens et al. found that 1, 8- cineole can inhibit the release of PGE2 and lt B4 from peripheral blood mononuclear cells of asthmatic patients, and can inhibit the release of cytokines and inflammatory mediators such as TNF-α, IL- 1, LTB4 and thromboxane B2 from peripheral blood mononuclear cells of healthy people stimulated by LPS [6]. In experiment [7], it was found that eucalyptus globulus oil can significantly reduce the total number of cells, the proportion of neutrophils and lymphocytes in lung lavage fluid of rats with chronic bronchitis caused by lipopolysaccharide, and it can be observed in pathological sections that eucalyptus globulus oil can significantly inhibit bronchiolitis and interstitial inflammation of lung caused by LPS and reduce inflammatory cell infiltration around airway.
1.3 Improve respiratory function [8,9]. Its main functions are: alkalizing mucus, reducing viscosity and restoring pH value to normal value; Regulate secretion, restore the ratio of serous fluid to mucus, and provide normal cilia swing space; β -parasympathetic nerve directly stimulates cilia to swing and accelerates mucus movement. Enhance the function of removing mucus and cilia.
1.4 Anti-parasite [10] Li Jianhua and others studied the repellent effect of eucalyptus oil on several parasites. The results showed that eucalyptus oil had a strong killing effect on demodex and trichomonas. 5% eucalyptus oil has obvious repellent effect on Anopheles sinensis, Culex pipiens quinquefasciatus and Aedes albopictus, and the effect intensity is positively related to its drug concentration and drug action time. The study on the anti-parasitic effect of eucalyptus oil will contribute to the further development and utilization of medicinal plant resources in China.
1.5 promoting transdermal absorption [1 1] Free fatty acids in the skin lipid layer can form a layered liquid crystal structure under appropriate conditions, and another Maltese cross-shaped liquid crystal can be formed after adding cholesterol and proper saponification. Eucalyptus oil, a penetration enhancer, can change the liquid crystal structure. At higher concentration, eucalyptus oil permeates into the liquid crystal structure to disturb or even destroy the liquid crystal structure, but it does not affect the structure of lipid molecules, which may be one of the reasons why eucalyptus oil promotes the transdermal absorption of drugs.
1.6 Other eucalyptus oil also has the effects of expelling wind, relieving pain, relieving itching and relieving summer heat.