Silkworm bean disease is an acute hemolytic disease that occurs after people with hereditary deficiency of glucose phosphate dehydrogenase (G6PD enzyme) eat broad beans, also known as bean yellow and broad bean yellow. It is common in children, especially in boys under 5 years old, accounting for about 90%. It often occurs in the mature season of broad beans, and eating broad beans or broad bean products (such as vermicelli and soy sauce) can cause diseases.

Patients usually get sick within 24 ~ 48 hours after eating broad beans, showing acute intravascular hemolysis, general malaise, fever, nausea, vomiting, rapid anemia, jaundice and hemoglobinuria, and severe hemolysis leads to shock, oliguria, anuria, acidosis and acute renal failure. Whether it comes on or not, the severity of the disease has nothing to do with the number of broad beans eaten. Sometimes eating1~ 2 grains is hard to escape, sometimes it can come on by inhaling or contacting broad bean pollen, and even sometimes the wet nurse can get sick by eating broad beans through milk.

The anemia degree and symptoms of this disease are mostly serious. Symptoms in general cases last for 2 ~ 6 days. If anemia, hypoxia and electrolyte imbalance are not corrected in time, it can be fatal; But if treated in time, you can get rid of danger and recover. In low-incidence areas, this disease is easily overlooked and missed diagnosis.